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No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

Finasteride may cause male infertility, stopping it can help.

Patient had scalp allergy from minoxidil; test helped identify cause and suggest alternative treatments.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

A male with aromatase deficiency improved bone health with estradiol treatment.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

High doses of finasteride cause cell growth and tumors in mice.

Minoxidil may cause heart issues in animals and humans.

Finasteride may worsen infertility in men with existing issues, but stopping it can improve sperm health.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

Sarcoptes scabiei infection causes significant health and behavior changes in wombats.

Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.

Finasteride can cause one-sided breast enlargement, which disappears after stopping the drug.

Finasteride doesn't affect hormone levels in normal men.