research Cutaneous Responses to Systemic Iron: A Potential Role for Epidermal Turnover in Mammalian Iron Excretion
Skin may help in getting rid of excess iron through the process of skin cell renewal.
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research Epidermal Stem Cell Diversity and Quiescence
Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.
research From Structural Resilience to Cell Specification: Intermediate Filaments as Regulators of Cell Fate
Intermediate filaments are crucial for cell differentiation and stem cell function.
research Immunolocalization of a Histidine-Rich Epidermal Differentiation Protein in the Chicken Supports the Hypothesis of an Evolutionary Developmental Link Between the Embryonic Subperiderm and Feather Barbs and Barbules
A specific protein in chicken embryos links early skin layers to feather development.
research Signaling Involved in Hair Follicle Morphogenesis and Development
The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
research IL-33 Contributes to the Pathological Changes of Hair Follicles in Psoriasis: A Potential Target for Psoriatic Alopecia
IL-33 is linked to hair follicle damage in psoriasis and could be a treatment target for hair loss in this condition.
research Exogenous Stimulation with Eclipta Alba Promotes Hair Matrix Keratinocyte Proliferation and Downregulates TGF-β1 Expression in Nude Mice
Eclipta alba extract helps increase hair growth and decrease hair loss-related protein in mice.
research Keratinocytes and Adipose-Derived Mesenchymal Stem Cells: The Heir and the Spare to Regenerative Cellular Therapies for Difficult-to-Heal Skin Wounds
Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.
research Vitamin D and the Skin
research Wnt/β-Catenin Signaling Stabilizes Hemidesmosomes in Keratinocytes
Wnt/β-catenin signaling is important for keeping skin cell attachment structures stable.
research Pleiotropic Role of Notch Signaling in Human Skin Diseases
Notch signaling disruptions can cause various skin diseases.
research Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis
Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.
research WNT Signaling in the Control of Hair Growth and Structure
The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.
research Marked Reduction of the Number and Individual Volume of Sebaceous Glands in Psoriatic Lesions
Psoriasis lesions have fewer and smaller oil glands, which might affect the condition's development.
research Single-Cell Transcriptomics Reveals the Molecular Anatomy of Sheep Hair Follicle Heterogeneity and Wool Curvature
The research identified genes that explain why some sheep have curly wool and others have straight wool.
research Vitamin D Metabolism and Function in the Skin
Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.
research CD98hc (SLC3A2) Regulation of Skin Homeostasis Wanes With Age
CD98hc's role in skin health decreases with age.
research Filling Injection of Platelet-Rich Plasma Gel as a New Method to Treat En Coup de Sabre Scleroderma
Platelet-rich Plasma Gel may help treat en coup de sabre scleroderma, improving symptoms and skin quality with minimal side effects.
research Role of the ABCA4 Gene Expression in the Clearance of Toxic Vitamin A Derivatives in Human Hair Follicle Stem Cells and Keratinocytes
The ABCA4 gene protects hair follicle stem cells from toxic vitamin A byproducts.
research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Different types of skin cells play specific roles in development, healing, and cancer.
research Type XVII Collagen Coordinates Proliferation in the Interfollicular Epidermis
Type XVII collagen helps control skin cell growth and could be a target for anti-aging treatments.
research Inducible Deletion of Epidermal Dicer and Drosha Reveals Multiple Functions for miRNAs in Postnatal Skin
Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
research The G60S Connexin43 Mutant Regulates Hair Growth and Hair Fiber Morphology in a Mouse Model of Human Oculodentodigital Dysplasia
The G60S Connexin43 mutation causes hair growth issues and poor hair quality in mice, similar to human ODDD patients.
research Hyaluronic Acid-FGF2-Derived Peptide Bioconjugates for Suppression of FGFR2 and AR Simultaneously as an Acne Antagonist
The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.
research Adipocytes in Skin Health and Disease
Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
research Concise Review: Wnt Signaling Pathways in Skin Development and Epidermal Stem Cells
Wnt signaling is crucial for skin development and hair growth.
research Targeting the Stem Cell Niche: Role of Collagen XVII in Skin Aging and Wound Repair
Collagen XVII is important for skin aging and wound healing.
research Expression and Functional Relevance of Melatonin Receptors in Hair Follicle Biology
Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.
research Defining the Transcriptional Signature of Esophageal-to-Skin Lineage Conversion
Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.
research Cytochrome P450: A Target for Drug Development for Skin Diseases
Modulating Cytochrome P450 activity could help develop new skin disease treatments.