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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Telogen effluvium is a reversible hair loss condition that requires a detailed diagnosis and often resolves on its own.

Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Noggin is necessary to start the hair growth phase in skin after birth.

Finasteride effectively treats BPH, but needs more trials to understand potential.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Oxidative stress causes hair to gray by damaging and killing pigment cells.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Platelet-rich plasma treatment significantly increased hair regrowth and decreased discomfort in alopecia patients, making it a potentially better and safer treatment option.

Liposomes and niosomes can help drugs penetrate the skin better.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Microneedles are being used and tested for various medical and cosmetic treatments.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

Women are more likely to have long-term post-COVID symptoms than men.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

The cuneate nucleus has two main neuron types: relay neurons and interneurons.