research Acne-Associated Syndromes
Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.
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research Imaging Nanoscale Changes in Desmosome Protein Organization
Desmoglein 3 organization in cell connections changes without calcium, affecting cell adhesion.
research 2-Substituted 4-(Thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase
New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
research The Pathogenesis of Primary Cicatricial Alopecias
The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
research A Novel Therapeutic Paradigm for Patients with Extensive Alopecia Areata
New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.
research Non-Infective Mucocutaneous Presentations of Human Immunodeficiency Virus Infection
Most HIV patients develop skin symptoms that can indicate the stage of their disease.
research An Urticarial Drug Eruption Caused by Tofacitinib for Alopecia Universalis
A patient with alopecia had hair regrowth with tofacitinib but developed a skin reaction, choosing to continue the treatment despite the side effect.
research ESGCT and FSGT Collaborative Congress Helsinki, Finland September 17–20, 2015 Abstracts
The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.
research Alopecia Areata Is Characterized by Dysregulation in Systemic Type 17 and Type 2 Cytokines, Which May Contribute to Disease-Associated Psychological Morbidity
Alopecia areata involves immune system imbalances that may lead to depression and anxiety.
research Identifying Key Components and Therapeutic Targets of the Immune System in Hidradenitis Suppurativa with an Emphasis on Neutrophils
The article suggests that targeting specific immune pathways could help control and treat the skin disease hidradenitis suppurativa.
research A Comparative Analysis of Immune Privilege in Pregnancy and Cancer in the Context of Checkpoint Blockade Immunotherapy
The document concludes that pregnancy and cancer share immune evasion tactics, but more research is needed before using checkpoint blockade immunotherapy in pregnant cancer patients to avoid harm to the placenta.
research Single-Cell Transcriptomics Reveals Lineage Trajectory of Human Scalp Hair Follicle and Informs Mechanisms of Hair Graying
The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.
research What's New in Dermatological Research?
2011 dermatological research found new skin aging markers, hair loss causes, skin defense mechanisms, and potential for new treatments.
research Individual Variation in Balance Between Platelet-Secreted Growth Factors Causing Contradictory Effects on Hair Follicle Could Potentially Impact Response to PRP Therapy in Patients With Scalp Hair Loss
People respond differently to hair loss treatment with PRP because of individual differences in growth factors from platelets.
research TRP Channels in Skin Biology and Pathophysiology
TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
research The Pathogenesis of Alopecia Areata
Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.
research Review of Scalp Alopecia Due to a Clinically Unapparent or Minimally Apparent Neoplasm (SACUMAN)
SACUMAN, a rare condition causing hair loss without clear signs, is often misdiagnosed and needs scalp biopsies for accurate detection.
research New Drugs Under Investigation for the Treatment of Alopecias
New treatments for hair loss show promise, but more research is needed to confirm their safety and effectiveness.
research Pathophysiology of Burn Scars
Burn scars form abnormally due to changes in wound healing, and more research is needed to improve treatments.
research Prostaglandin D2 Inhibits Wound-Induced Hair Follicle Neogenesis Through the Receptor Gpr44
Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.
research Skin Diseases Associated With Atopic Dermatitis
People with atopic dermatitis are more likely to develop other skin conditions due to shared genetics and immune pathways.
research Cancer Risk by the Subtype of Alopecia
People with certain types of alopecia have a slightly higher risk of cancer, especially thyroid, bladder, and prostate cancers.
research Follicular Neutrophilic Inflammation in Hidradenitis Suppurativa
Hidradenitis Suppurativa is likely an autoinflammatory disease, and better understanding its causes could improve treatments.
research Skin Disease in Pregnancy
Some skin conditions are common during pregnancy and can be safely treated without affecting the pregnancy outcome.
research Integration of Magnetic Tweezers and Traction Force Microscopy for Exploring the Mechanobiology of Keratinocyte Cell-Cell and Cell-Matrix Anchoring Junctions
The conclusion is that a new method combining magnetic tweezers and traction force microscopy may help understand skin cell interactions and diseases.
research Elevated Expression of Osteopontin Splice Variants in Nonmelanoma Skin Cancer Compared to Normal Skin and Adult Keratinocytes
Nonmelanoma skin cancers have higher levels of certain osteopontin variants than normal skin.
research COVID-19 and Sex Differences: Mechanisms and Biomarkers
Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.
research Zinc: A Complementary Factor in the Treatment of Chronic Hepatitis C?
Zinc supplementation may help improve treatment outcomes for chronic hepatitis C.
research Integral Roles of Specific Proteoglycans in Hair Growth and Hair Loss: Mechanisms Behind the Bioactivity of Proteoglycan Replacement Therapy with Nourkrin with Marilex in Pattern Hair Loss and Telogen Effluvium
Proteoglycans are important for hair growth, and a specific treatment can help reduce hair loss.
research Toll-Like Receptor Function in Acute Wounds
Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.