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Certain immune cells contribute to severe hair loss in chronic alopecia areata, with Th17 cells possibly having a bigger impact than cytotoxic T cells.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

JAK inhibitors like tofacitinib may effectively treat Alopecia Areata.

Regulatory T cells are essential for normal and improved wound healing in mice.

FLCN helps control iron levels in cells.

Skin healing from blisters can delay hair growth as stem cells focus on repairing skin over developing hair.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Treg cells help repair and regenerate tissues by interacting with local cells.

Exosome treatment for hair growth is promising but not FDA-approved and needs more research on safety and how it works.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

Aldesleukin can treat certain cancers and increase HIV patient CD4+ counts but often causes severe side effects.

The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.

Human body's immune cells are more common in the layer of fat just beneath the skin than in deeper fat layers.

A herbal extract may help treat certain types of hair loss by reducing a specific gene's activity.

Hair loss in a drug reaction case involved both a common shedding phase and an immune attack on hair follicle stem cells.

MCPIP1 in myeloid cells is important for skin cancer development and healthy hair growth.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.

Human umbilical cord stem cell vesicles may help treat aging and related diseases.

Autoimmune diseases cause the immune system to attack the body, and management varies as some are curable and others are not.

Higher CD70 and CD27 gene expression in alopecia areata lesions predicts disease severity and activity.

Autoimmune diseases cause the immune system to attack the body, and management varies as some are curable and others are not.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.

RXRα is crucial for proper immune response and links diet to immune function.

COVID-19 may harm male fertility and damage the reproductive system.

Fermented soy protein may help prevent bone loss by affecting bone cell activity.

Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.