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    Glossary SZ95 Sebocytes

    human sebaceous gland cells used in skin research

    SZ95 Sebocytes are a type of human sebaceous gland cell line used in scientific research. These cells are derived from sebaceous glands, which are responsible for producing sebum, an oily substance that helps keep the skin and hair moisturized. Researchers use SZ95 Sebocytes to study skin conditions, such as acne and alopecia, and to test the effects of various treatments on sebaceous gland function.

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    Research 30 of 112

    1. Effects of α-Synuclein on the Lipid Phenotype of SZ95 Human Sebocytes: A Preliminary Study in the Context of Parkinson’s Disease Cells · 2026
    2. Expression of dermcidin in sebocytes supports a role for sebum in the constitutive innate defense of human skin Journal of Dermatological Science · 2015 · 25 citations
    3. Sebocytes are the Key Regulators of Androgen Homeostasis in Human Skin 2001 · 196 citations
    4. Inhibition of the Androgen Receptor by Antisense Oligonucleotides Regulates the Biological Activity of Androgens in SZ95 Sebocytes Hormone and metabolic research · 2007 · 29 citations
    5. 605 3D-SeboSkin model application in Hidradenitis suppurativa/acne inversa Journal of Investigative Dermatology · 2019
    6. 196 The endocannabinoid tone regulates human sebocyte biology Journal of Investigative Dermatology · 2016
    7. 1321 Endocannabinoid-like molecule oleoylethanolamide promotes sebaceous lipid synthesis Journal of Investigative Dermatology · 2018 · 1 citations
    8. Inhibition of lipogenesis and sebum secretion for <i>Lotus corniculatus</i> seed extract in vitro and in vivo International Journal of Cosmetic Science · 2022 · 1 citations
    9. Expression of steroidogenic enzymes in human sebaceous glands 2014 · 25 citations
    10. Pharmacological Inhibition of Stearoyl CoA Desaturase in the Skin Induces Atrophy of the Sebaceous Glands 2013 · 25 citations
    11. プログラミング開発環境の変化と対策 (プログラム作りの環境 ) -- (実例:各社はこんな環境で生産性向上を図っている) ビジネスコミュニケ-ション · 1981
    12. 녹차추출물이 인체 피지선세포주에서 지질 생성에 미치는 효과 동의생리병리학회지 = Journal of physiology & pathology in Korean Medicine · 2011
    13. 1317 Nicotinic acid suppresses sebaceous lipid synthesis of human sebocytes via activating hydroxycarboxylic acid receptor 2 (HCA2) Journal of Investigative Dermatology · 2018
    14. 260 Establishment and characterization of human sebocytic progenitor cells that can differentiate into functional sebocytes Journal of Investigative Dermatology · 2017
    15. Adiponectin Signaling Regulates Lipid Production in Human Sebocytes PLoS ONE · 2017 · 32 citations
    16. Inhibition of Insulin-Like Growth Factor-1–Induced Sebum Production by Bilobetin in Cultured Human Sebocytes Annals of Dermatology · 2019 · 8 citations
    17. The TRPM5 Antagonist Triphenylphosphine Oxide Increases Sebaceous Lipogenesis and Modulates Immune Phenotype of Human Sebocytes in a TRPM5‐Independent Manner Experimental Dermatology · 2025
    18. Sebum Free Fatty Acids Enhance the Innate Immune Defense of Human Sebocytes by Upregulating β-Defensin-2 Expression Journal of Investigative Dermatology · 2009 · 195 citations
    19. Activation of TRPV3 Inhibits Lipogenesis and Stimulates Production of Inflammatory Mediators in Human Sebocytes—A Putative Contributor to Dry Skin Dermatoses Journal of Investigative Dermatology · 2018 · 26 citations
    20. Corticotropin-releasing hormone: An autocrine hormone that promotes lipogenesis in human sebocytes Proceedings of the National Academy of Sciences · 2002 · 284 citations
    21. “Sebocytes’ makeup” - Novel mechanisms and concepts in the physiology of the human sebaceous glands 2011 · 58 citations
    22. Short-Chain Fatty Acids from <i>Cutibacterium acnes</i> Activate Both a Canonical and Epigenetic Inflammatory Response in Human Sebocytes 2019 · 70 citations
    23. The human skin as a hormone target and an endocrine gland Hormones · 2004 · 146 citations
    24. Cidea Control of Lipid Storage and Secretion in Mouse and Human Sebaceous Glands Molecular and Cellular Biology · 2014 · 36 citations
    25. TGFβ signaling regulates lipogenesis in human sebaceous glands cells BMC Dermatology · 2013 · 44 citations
    26. Androgens induce sebaceous differentiation in sebocyte cells expressing a stable functional androgen receptor 2015 · 31 citations
    27. Integrated evaluation of umbilical cord mesenchymal stromal cell-derived extracellular vesicles across skin-related cellular and zebrafish models Frontiers in Bioengineering and Biotechnology · 2026
    28. Beyond acne: Current aspects of sebaceous gland biology and function Reviews in Endocrine and Metabolic Disorders · 2016 · 97 citations
    29. Mechanistic insights into 5-aminolevulinic acid photodynamic therapy for acne vulgaris: targeting lipogenesis via the OLR1-Wnt/β-catenin pathway Molecular Medicine · 2025 · 4 citations
    30. 910 Transepidermal UV radiation of human scalp skin induces distinctive hair follicle damage, which is mitigated by topical caffeine treatment Journal of Investigative Dermatology · 2019