May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review article examines recent advances in understanding and managing various types of alopecia, highlighting modern therapeutic strategies such as individualized treatment plans, combination therapies, and regenerative approaches aimed at improving hair regrowth and minimizing adverse effects.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review article reports on the latest therapeutic strategies for alopecia, highlighting advancements in personalized treatment plans, combination therapies, and regenerative approaches, with a focus on improving hair regrowth and minimizing side effects through modern treatments like stem cell therapy and Janus kinase inhibitors.
March 2026 in “Editora Pasteur eBooks” This study reviews hair follicle physiology and common scalp diseases such as androgenetic alopecia, telogen effluvium, and alopecia areata, highlighting their pathophysiology and current treatment approaches, which may include topical, systemic, and adjunctive therapies.
October 2025 in “JURNAL BIOLOGI TROPIS” This literature review found that androgenetic alopecia has a complex multifactorial etiology and effective management should be tailored to individual severity and gender to improve patients' quality of life.
January 2017 in “Springer eBooks” Over 40% of postmenopausal women experience hair loss, with treatments aiming to stop further loss and possibly thicken hair.
This study found that topical finasteride was absorbed into the bloodstream to a minimal extent in male rats, even with repeated applications, suggesting low systemic exposure.
August 2021 in “Annales pharmaceutiques françaises” This study used computer simulations to evaluate the absorption of oral and topical finasteride for treating androgenetic alopecia, finding that topical applications resulted in lower plasma concentrations, suggesting potential viability as a treatment option.
149 citations
,
July 2002 in “Dermatologic clinics” This review discusses the pathogenesis, clinical presentation, diagnosis, and treatment of cutaneous lupus erythematosus, reporting no new clinical findings.
41 citations
,
August 1988 in “Journal of The American Academy of Dermatology” In this case report, a patient with subacute cutaneous lupus erythematosus and exfoliative erythroderma achieved complete remission with systemic corticosteroids and long-term hydroxychloroquine.
39 citations
,
September 2017 in “The Open Rheumatology Journal” This review discusses the role of complement activation in SLE and suggests that while monitoring C3 and C4 remains important, increased levels of cell-bound complement activation products may better indicate disease activity.
12 citations
,
December 2021 in “Frontiers in Medicine” This study observed that dermatological patients using certain immunosuppressants, like azathioprine and high-dose prednisolone, had a reduced humoral immune response to the Sinovac-CoronaVac COVID-19 vaccine compared to those without such treatments.
May 2022 in “Annals of the Rheumatic Diseases” This case report describes two cases of systemic lupus erythematosus (SLE) onset occurring within two months after COVID-19 vaccination, but it remains unclear if the vaccination contributed to these cases.
December 2009 in “DergiPark (Istanbul University)” This study found that low levels of ferritin and iron were common among women with diffuse hair loss, suggesting these tests could be useful in evaluating such patients.
September 2025 in “International Journal of Innovative Technologies in Social Science” This review found that dutasteride is more effective than finasteride in increasing hair count and shaft thickness for androgenetic alopecia in men, with potential for reduced systemic side effects through mesotherapy, although further research is needed on long-term safety and dosage.
November 2011 in “Informa Healthcare eBooks” Environmental, chemical, mechanical, and personal health factors can all damage hair and contribute to hair loss or changes in hair quality.
7 citations
,
August 2017 in “Journal of Evolution of Medical and Dental Sciences” This study found that women with polycystic ovary syndrome had significantly higher levels of periodontal disease compared to women without the condition.
2 citations
,
April 2023 in “South East European Journal of Immunology” This pilot study found elevated levels of leptin and other proinflammatory molecules in the serum of melanoma patients, suggesting a potential role for leptin in melanoma progression and a possibility for targeting it in adjuvant therapy.
September 2023 in “Forum Dermatologicum” This source discusses androgenetic alopecia, noting that male patients may transition from topical minoxidil to its systemic form or from finasteride to dutasteride for potentially better results, while female patients might require extensive lab testing to identify hyperandrogenism due to environmental triggers.
March 2014 in “Journal of the American Academy of Dermatology” Alopecia areata is relatively common in children, has a variable course, and shows different responses to treatment; thyroid testing is recommended for those affected.
April 2017 in “Journal of Investigative Dermatology” In this study, higher plasma leptin levels were associated with increased risk and severity of androgenetic alopecia in men, but further research is needed to understand the clinical implications.
August 2019 in “Journal of Investigative Dermatology” This study suggests that epidermal turnover could be a regulated mechanism of iron excretion, with systemic iron levels influencing keratinocyte behavior and differentiation markers in the skin.
March 2026 in “Oral Presentations” This study identified hemoglobin level as the strongest biological predictor of fatigue in systemic lupus erythematosus patients, highlighting its association with disease activity and systemic inflammation.
April 2025 in “Dermatology Practical & Conceptual” This study found that patients with alopecia areata had significantly higher systemic immune-inflammation index levels compared to healthy controls, regardless of the disease's severity.
July 1996 in “Clinical and Experimental Dermatology” This study found that a single topical application of calcipotriol ointment did not affect systemic calcium levels in patients with chronic plaque psoriasis.
19 citations
,
September 2010 in “The American journal of pathology” This study demonstrated that elevated glucocorticoid levels in transgenic mice led to pancreatic exocrine cells transforming into hepatocyte-like cells, resulting in pancreatic dysfunction.
8 citations
,
January 2008 in “Annals of Dermatology” This study concluded that combining systemic cyclosporine A with low-dose corticosteroids effectively treats severe alopecia areata while maintaining safe cyclosporine A levels in the blood.
567 citations
,
October 2007 in “Clinical and investigative medicine” This study described a new assay for measuring cortisol in hair and found it may serve as a useful biomarker for long-term cortisol exposure, correlating with 24-hour urine cortisol levels in non-obese subjects.
16 citations
,
April 2006 in “Pediatrics International” This study reported that high-dose mizoribin therapy may be effective and safe for managing steroid-dependent pediatric systemic lupus erythematosus but requires monitoring of serum uric acid levels due to potential side effects.
In this study, researchers found that patients with alopecia areata displayed higher systemic inflammatory markers and lower vitamin D levels compared to healthy controls, yet they exhibited similar cardiovascular risk profiles, with no association between inflammation and cardiovascular risk or alopecia severity.
May 2024 in “International journal of medicine and psychology.” This study found that patients with chronic-stage true eczema and comorbid depression experienced a more severe disease progression, marked by higher inflammation levels and significantly reduced quality of life compared to those without depression.