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    Glossary Systemic Inflammation

    widespread inflammatory response affecting the entire body

    Systemic inflammation is a widespread inflammatory response that affects the entire body, rather than being localized to a specific area. It can be triggered by infections, chronic diseases, or autoimmune conditions, leading to symptoms like fever, fatigue, and elevated levels of inflammatory markers in the blood. This type of inflammation is significant because it can contribute to the development of various health issues, including cardiovascular diseases and metabolic disorders.

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    1. Complete Blood Collection-based Systemic Inflammation Biomarkers as a Severity Biomarker in Alopecia Areata: A Cross-sectional Study Acta Dermato Venereologica · 2024 · 7 citations
    2. Relationship between hair shedding and systemic inflammation in COVID-19 pneumonia Annals of Medicine · 2022 · 3 citations
    3. Iron Deficiency in Immune-Mediated Inflammatory Skin Diseases: A Missing Link Between Systemic Inflammation, Immunometabolism, and Disease Burden Cells · 2026
    4. Cardiovascular Risk and Systemic Inflammation in Alopecia Areata: An Observational Case-control Study. PubMed · 2025
    5. 51826 PRO-C22 - A Novel Serological Biomarker of Tissue Damage is Associated with Disease Severity, Disease Activity, and Systemic Inflammation in Patients with Hidradenitis Suppurativa Journal of the American Academy of Dermatology · 2024
    6. Systemic Inflammation Marker Alterations in Severe Alopecia Areata Patients Treated with Janus Kinase Inhibitors Journal of Clinical Medicine · 2026
    7. Systemic Inflammatory Biomarkers in Alopecia Areata: The Role of SII, SIRI, and CRP/Albumin Ratio Dermatology Practical & Conceptual · 2025
    8. Association Between Scalp Microbiota Imbalance, Disease Severity, and Systemic Inflammatory Markers in Alopecia Areata Dermatology and Therapy · 2024 · 4 citations
    9. Case Report: High Dose Vitamin D & Anti-inflammatory Diet (Systemic Lupus Erythematosus & Alopecia Areata) Zenodo (CERN European Organization for Nuclear Research) · 2023
    10. Adjunct Treatment with Platelet-rich Plasma for the Treatment of Inflammatory Alopecia in an Adult Filipino Female with Systemic Lupus Erythematosus Deleted Journal · 2024
    11. Systemic Lupus Erythematosus With Acute Inflammatory Demyelinating Polyneuropathy: A Case Report and Review of the Literature Journal of Clinical Medicine Research · 2016 · 18 citations
    12. Exploring the Impact of Systemic Inflammatory Regulators on Rosacea Risk: A Bidirectional Mendelian Randomization Analysis Clinical Cosmetic and Investigational Dermatology · 2025 · 1 citations
    13. The Association Between Low Grade Systemic Inflammation and Skin Diseases: A Cross-sectional Survey in the Northern Finland Birth Cohort 1966 Acta dermato-venereologica · 2017 · 27 citations
    14. Lipid Modulation and Systemic Inflammation Critical care clinics · 2001 · 33 citations
    15. Androgenetic Alopecia in Polycystic Ovary Syndrome: A Cutaneous Marker of Systemic Metabo-inflammatory and Endocrine Dysfunction: A Narrative Review Endocrine Connections · 2026
    16. Abstract 18: Targeted epidermal ablation of EGFR causes local and systemic inflammation Cancer Research · 2010 · 2 citations
    17. S2:04 Decoding fatigue in systemic lupus erythematosus with artificial intelligence: hematologic or inflammatory factors? Oral Presentations · 2026
    18. Polycystic ovary syndrome (PCOS), an inflammatory, systemic, lifestyle endocrinopathy 2018 · 317 citations
    19. Association between geriatric nutritional risk index and fecal incontinence in individuals with stroke: mediating roles of systemic immune inflammation index and oxidative balance scores Frontiers in Nutrition · 2025
    20. Mitochondrial Complex I Activity Suppresses Inflammation and Enhances Bone Resorption by Shifting Macrophage-Osteoclast Polarization Cell Metabolism · 2014 · 222 citations
    21. Regulation of Epidermal Ferritin Expression Influences Systemic Iron Homeostasis Journal of Investigative Dermatology · 2023 · 6 citations
    22. Biochemical Alterations and Immune-Inflammatory Responses in Alopecia Areata: A Case-Control Study kerbala journal of pharmaceutical sciences · 2026
    23. Serum level of calprotectin as a new inflammatory marker in patients with alopacia areata Egyptian journal of Immunology · 2025
    24. Features of the clinical course of the disease, quality of life and systemic cytokine profile in patients with chronic true eczema and depression International journal of medicine and psychology. · 2024
    25. Retrospective Comparison of Inflammatory Markers in Severe Acne Vulgaris Patients and Normal Population Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi · 2026
    26. Non-scarring patchy alopecia in patients with systemic lupus erythematosus differs from that of alopecia areata Lupus · 2013 · 30 citations
    27. Systemic dexpanthenol as a novel treatment for female pattern hair loss Journal of Cosmetic Dermatology · 2020 · 5 citations
    28. Systemic Circulating Leptin – Aiding New Dimension of Immune-Related Skin Carcinogenesis and Lipid Metabolism South East European Journal of Immunology · 2023 · 2 citations
    29. Divergence between initial and cumulative manifestations in systemic lupus erythematosus: effect of age and sex in a prospective lupus cohort from Pakistan Annals of Medicine and Surgery · 2026
    30. Approved systemic drugs needed for dermatosis like alopecia areata, hidradenitis and vitiligo: A SPIN‐FRT evaluation Journal of the European Academy of Dermatology and Venereology · 2024