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Topical metformin shows promise for dental and skin treatments, including periodontitis, hair regrowth, wound healing, and acne.

JAK inhibitors effectively improve hair regrowth in alopecia areata with an acceptable safety profile.

Leflunomide and methotrexate are similarly effective for rheumatoid arthritis but have different side effects.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Medications for hair loss and prostate issues can significantly increase the risk of sexual side effects and other negative symptoms.

Most cutaneous adnexal tumors examined were benign and resembled common skin tumors.

Satoyoshi syndrome is likely an autoimmune disease that mainly affects young women and improves with immune-related treatments.

Fractional lasers effectively treat alopecia areata, especially when combined with minoxidil or cortisol.

Chemotherapy may help with survival in children with medulloblastoma, but more research is needed.

PRP is an effective and safe treatment for female hair loss.

More research is needed to find effective treatments for sickle cell disease-related priapism.

Contact immunotherapy might help treat various skin conditions, but more research is needed to confirm its safety and effectiveness.

Oral JAK inhibitors are effective and safe for treating alopecia areata but may need ongoing use to keep results.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might decrease the risk. AST also lessens the chance of cancer coming back but doesn't really affect survival rates. More research is needed to understand AST's benefits for different bladder cancers.

Platelet-rich plasma injections effectively increase hair density in men suffering from common hair loss.

The document concludes that improving patient safety and quality is increasingly important in dermatology.

Taking 5-alpha reductase inhibitors does not increase breast cancer risk in men.

People with certain skin conditions, especially androgenic alopecia, are more likely to have metabolic syndrome.

Chromium supplements don't help with weight loss or improve hormone and metabolism issues in people with polycystic ovary syndrome.

The review found that current care models for PCOS are not fully effective and more research is needed, especially in low-income countries.

Janus kinase inhibitors can regrow hair in alopecia areata but may cause side effects and hair loss may return if treatment stops.

PRP treatment increases hair density and thickness in androgenetic alopecia by 79%.

Androgenetic alopecia causes significant psychological distress, especially in women, and requires both medical and psychological support.

Gender-affirming dermatology treatments generally improve mental well-being for transgender individuals, but more research is needed.

Androgenetic alopecia negatively affects quality of life and self-esteem, especially in women, but not depression.

Platelet-rich plasma (PRP) may improve healing in chronic wounds and vitiligo and promote hair regrowth, but more research is needed.

JAK-inhibitors for alopecia areata are generally safe with mostly mild side effects and a low rate of treatment withdrawal.

Chitosan-based dressings reduce inflammation and speed up skin wound healing.

Low-level laser therapy can stimulate hair growth more effectively than fake devices, but patient satisfaction is similar for both. Results should be taken with caution due to small study sizes and differences between studies. More research is needed.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might reduce it. AST decreases recurrence-free survival but doesn't affect overall survival or progression-free survival. More research is needed to understand AST's benefits.