82 citations
,
May 2010 in “PLoS neglected tropical diseases” This study provides quantitative evidence that secondary syphilis is highly endemic in Cali, Colombia, and many untreated patients have high numbers of circulating Treponema pallidum spirochetes.
12 citations
,
October 1976 in “The BMJ” This abstract reports an influenzalike illness with varying antibody titers observed in a woman and her husband, but it does not provide broader clinical findings.
10 citations
,
July 2012 in “International Journal of Dermatology” This article addresses diffuse pattern essential syphilitic alopecia as an unusual form of secondary syphilis but provides no new clinical findings.
6 citations
,
April 2015 in “Infection” This case study describes a patient with secondary syphilis, including alopecia syphilitica diffusa, whose symptoms resolved completely after treatment with benzylpenicillin following prednisolone prophylaxis.
3 citations
,
June 2015 in “Serbian Journal of Dermatology and Venereology” In this study, secondary syphilis presented diverse clinical manifestations, with syphilitic alopecia occurring only in HIV-positive patients, underscoring the importance of considering syphilis in differential diagnoses for vulnerable populations.
1 citations
,
July 2024 in “Indian Journal of Sexually Transmitted Diseases and AIDS” In this study, a 38-year-old male with syphilis-related mixed pattern alopecia showed marked hair regrowth and resolution of postauricular lymphadenopathy after treatment with benzathine penicillin, suggesting that lymph node and hair examinations, along with trichoscopy, can aid in the diagnosis of alopecia syphilitica.
January 2021 in “Our Dermatology Online” This case report discusses alopecia syphilitica in a young Belgian man, notes that hair loss was his only symptom, and highlights the improvement following penicillin treatment.
December 2020 in “Journal of clinical and investigative dermatology” This case study highlights the rare simultaneous presentation of syphilitic alopecia and neurosyphilis in a 61-year-old man, underscoring the importance of recognizing this combination for timely treatment.
2 citations
,
April 2024 in “AIDS Research and Therapy” This case highlights the importance of considering syphilis testing for patients with unusual symptoms like hair loss and hypopigmentation, emphasizing the diagnostic and management challenges in resource-limited settings.
1 citations
,
July 2021 in “Clinical Cosmetic and Investigational Dermatology” This case study reports a misdiagnosis of secondary syphilis with probable neurosyphilis as PLEVA in a 12-year-old, highlighting the importance of considering syphilis in patients with unusual symptoms.
32 citations
,
January 2015 in “Annals of diagnostic pathology” This study highlights the importance of recognizing oral lesions in diagnosing syphilis, as illustrated by three reported cases.
September 2009 in “Jagiellonian University Repository (Jagiellonian University)” This article discusses hair loss as a clinical symptom of a specific condition known as "the great imitator," but provides no new research findings.
May 1993 in “Current problems in dermatology” This review discusses diagnostic approaches for childhood skin diseases with fever through clinical observations and covers recent advances in understanding the pathogenesis and epidemiology of related infections, without reporting new clinical results.
2 citations
,
January 1908 in “Journal of the American Medical Association” Fear of hair-related issues causes significant mental distress, especially in high-stress women.
January 2015 in “Indian Dermatology Online Journal” This diagnostic discussion reports that diffuse alopecia areata was identified in a patient with diffuse hair loss, based on specific histopathological features observed in a biopsy.
May 1948 in “Journal of the American Medical Association” The reply suggests checking for false positive or asymptomatic syphilis and using penicillin for treatment if necessary.
24 citations
,
July 1987 in “Dermatologic Clinics” This article reviews various causes of hair loss linked to systemic factors, noting that careful history and examination can lead to accurate diagnosis, but reports no new clinical results.
11 citations
,
May 2020 in “Anais Brasileiros de Dermatologia” This case report describes a patient with secondary syphilis exhibiting distinct dermoscopic features, including moth-eaten alopecia and an erythematous background more pronounced than previously reported.
6 citations
,
October 2012 in “BMJ” This case report describes a 37-year-old woman whose recurrent hair shedding was associated with low iron stores and a miscarriage, with improvements seen after increased iron intake.
4 citations
,
May 2022 in “Frontiers in Medicine” The authors concluded that trichoscopic examination can be useful for diagnosing syphilitic alopecia in patients with idiopathic alopecia, though the findings are nonspecific and further studies are needed.
2 citations
,
July 1993 in “JAMA” This article illustrates the impact of direct-to-consumer drug advertising through a case where a patient sought Rogaine for hair loss without medical assessment, revealing secondary syphilis-related symptoms instead.
1 citations
,
December 2010 in “InnovAiT” This article reviews common causes of hair loss and hair excess and discusses their management in primary care settings, but it reports no new clinical results.
January 2025 in “NATIONAL BOARD OF EXAMINATIONS JOURNAL OF MEDICAL SCIENCES” This case series reports the specific dermoscopic features observed in two patients with syphilitic alopecia, highlighting alopecic patches with empty hair follicles and other distinguishing characteristics that may aid in differentiating it from other hair disorders.
April 2015 in “Journal of the American Academy of Dermatology” This case study suggests that the most likely diagnosis for the patient with a pink, scaling rash is secondary syphilis.
June 2025 in “American Journal of Dermatopathology” This case report describes a rare instance of sarcoidal granulomatous alopecia areata in a 42-year-old man, with histopathological findings suggesting inflammation but ruling out causes like tuberculosis and syphilis, resulting in treatment with tofacitinib.
April 1940 in “Archives of dermatology” This abstract presents a case of arsenical dermatitis with pigmentation and alopecia developed during treatment with arsphenamine for a positive Wassermann reaction.
13 citations
,
June 2013 in “Actas Dermo-Sifiliográficas” This review details five cases of syphilitic alopecia, an uncommon symptom in syphilis affecting mainly men, emphasizing that dermatologists should be vigilant as it can appear as the sole symptom.
1 citations
,
January 2000 in “Springer eBooks” This review discusses the evaluation of skin conditions during pregnancy and emphasizes the importance of testing for syphilis, but it reports no new clinical results.
November 2012 in “South African Family Practice” This article describes the phases of the hair cycle in detail but reports no new clinical findings or results related to alopecia.
3 citations
,
February 2022 in “Cureus” This study observed an alopecia syphilitica-like pattern of hair loss in a woman with frontal fibrosing alopecia, suggesting it may be another atypical presentation of the condition.