Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, researchers found that circERCC6, a circular RNA identified in cashmere goat hair follicles, helps activate secondary hair follicle stem cells, with its role dependent on specific m6A modifications that interact with miR-412-3p to regulate BNC2 expression.

This study observed that Ayurveda Shamana therapy showed promising results in reducing the severity of androgenic alopecia symptoms without adverse effects.

This review discusses the potential role of thyroid receptor β agonists in treating androgenetic alopecia, reporting no new clinical results while highlighting their mechanism and anti-alopecia efficacy.

In this study, researchers analyzed the skin proteome of Alpine Merino sheep to identify proteins and pathways related to wool fiber diameter, finding that cyclic adenosine monophosphate and certain signaling pathways may play a role in this trait.

This study introduced a novel method that uses upright structured illumination microscopy and atomic force microscopy to map the mechanical properties of thick living tissue slices, revealing the intricate mechanical heterogeneity of mouse skin and effects of preservation techniques on tissue stiffness.

This study hypothesizes that the curling of hair may result from the contraction of the Arrector Pili Muscle, contributing to the diverse types of curly hair.

This review discusses the various components essential for successful tissue engineering, such as cell sources, modification methods, and supportive matrices, and highlights the need for functional synergy without reporting new experimental results.

This study found that CRISPR/Cas9-induced loss-of-function mutations in the FGF5 gene significantly increased wool length and yield in genetically modified Chinese Merino sheep compared to wild-type controls.

This review explores the potential impact of nutrition on immune-mediated inflammatory skin diseases and evaluates whether dietary changes could help in treatment planning, but it presents no new clinical outcomes.

In this study, overexpression of secretory phospholipase A2 Group-IIA in transgenic mice led to depletion of hair follicle stem cells and increased differentiation, linked to changes in histone modifications.

This study mapped the genome-wide epigenetic landscape in secondary hair follicle stem cells of goats, revealing distinct histone modification signatures associated with cashmere fiber cycling during different stages of hair growth.

This review examines the genetics of acne vulgaris, concluding that stem/progenitor cell maintenance and cellular migration are key processes in its pathogenesis, potentially shifting future treatment strategies beyond traditional antibiotics and retinoids, which have notable side effects.

This study developed a deep learning-based tool to quantify individual hair fibers in mice, revealing distinct hair phenotypes linked to hormonal, genetic, and age-related factors, and suggesting its potential for new diagnostic methods through hair analysis.

This study reported that reprogramming keratinocytes from plucked hair provides an easy, non-invasive, and efficient method for generating pluripotent iPSCs without the need for medical professionals or operating rooms.

This review discusses biotin and biotinidase deficiencies, their symptoms, and methods of medical management, without presenting new clinical findings.

This review examines the chemical composition and potential health risks of hair straighteners, but it reports no new findings and emphasizes the importance of understanding hair fibre structure for safe use.

This study identified a new S100 fused-type protein, scaffoldin, in reptiles and birds and suggests that SFTP-positive epithelia serve as scaffolds for the growth of various skin appendages, indicating a common evolutionary origin.

This study reviews the biology and cosmetic treatment of hair, emphasizing future advancements in safer, more effective procedures to meet consumer needs for hair care.

This article reviews extensive genetic polymorphisms in the keratin-associated proteins of human hair, indicating complexity but reporting no new clinical results and calls for further research on their potential impact on hair structure.

In this study, researchers found that size polymorphisms in certain hKAP1 genes are linked to the hKAP1.1B and hKAP1.3 genes, arising from intragenic deletions and duplications in Japanese and Caucasian populations.

Keratin patterns in hair follicles help understand hair growth and potential hair and nail disorders.

This study found that keratin 17 expression is initially down-regulated and later strongly up-regulated by ionizing radiation in a rat model, with p53 repressing early transcription.

This study comprehensively compared different crystalline forms of finasteride, including the new finasteride DMF solvate hemihydrate, to better understand their structural characteristics and intermolecular interactions.

This study suggests that distinct chromatin topologies allow different lineage-specific enhancers to regulate Hoxd genes in mouse vibrissae and chicken feather primordia, while conserved regulatory elements maintain transcriptional robustness in the embryonic trunk across species.

This study reveals that transglutaminase activity is widespread in integumentary structures of mammals and birds, suggesting it plays a significant role in the cornification of hard skin appendages like nails and feathers.

This review discusses the formation and structure of the cornified cell envelope in the epidermis, highlighting biochemical pathways and genetic factors, but presents no new experimental results.

This review explores the potential of cell-mediated drug delivery systems in dermatology, highlighting their ability to target inflamed or diseased skin while discussing applications in diseases like atopic dermatitis and melanoma, along with challenges such as immunogenicity and manufacturing.

This study found that the acidic hair straightening formulation at pH 1.0 improved hair alignments and straightening effectiveness more than pH 2.0, but it weakened fiber strength and affected hair color and composition.

This review highlights recent developments in nanovesicular carriers for enhancing molecule delivery into and across the skin, focusing on the design and evolution of phospholipid and non-phospholipid systems used in cosmetics and treating various skin conditions.

This paper reviews strategies for modifying the structure and protein delivery of electrospun nanofibrous materials, emphasizing their potential to guide tissue repair and highlighting current challenges and future research directions in this emerging field.