October 2008 in “Journal of Intellectual Property Law & Practice” The article concludes that recent legal rulings have strengthened the protection of pharmaceutical patents against generic competition.
June 2006 in “Almustansiriya journal of pharmaceutical sciences/Al-Mustansiriyah journal of pharmaceutical sciences” This study found that melatonin may reduce the dose of prednisone needed for treating alopecia areata and its associated side effects by attenuating free radical damage on the immune system.
January 2004 in “Analytical Sciences: X-ray Structure Analysis Online” This study reports the crystal structure of C28H32O5, revealing its monoclinic symmetry, unit-cell dimensions, and molecular conformation.
January 2003 in “Annals of Dermatology” This case report describes a hair structure abnormality associated with iron deficiency anemia, which improved after iron supplementation ceased hair loss and corrected the hair shaft abnormality.
August 2002 in “Analytical Sciences” The document concludes that a compound with potential for treating prostate cancer and hair loss was successfully made and its detailed structure was confirmed.
November 2001 in “PubMed” This research found that perming, combing, and stretching cause hair damage, leading to a significant reduction in keratin levels within a specific molecular weight range.
February 1999 in “Analytical Sciences” A new antiandrogen compound was made and its detailed three-dimensional shape was described.
This study demonstrates that the trichohyalin gene is located at chromosomal region 1q21, where several other genes related to epidermal differentiation also map.
December 1991 in “Annals of the New York Academy of Sciences” This article discusses themes in the molecular structure of hair and reports no new research findings.
January 1974 in “OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)” This study found that hair follicle melanocytes show increased age-related susceptibility to oxidative stress compared to epidermal melanocytes, which may contribute to the graying of hair.
October 2022 in “Biomedicines” In this rat study, offspring from females fertilized by finasteride-treated males showed hyperglycemia and increased hepatic glycogen, linking paternal androgen imbalance to liver issues across generations.
January 2022 in “International Journal of Health Science” The authors of this study aim to evaluate the strategies for using topical products in treating androgenetic alopecia, highlighting topical applications as potentially more effective and convenient compared to oral medications, which often suffer from poor patient adherence.
October 2021 in “QJM: An International Journal of Medicine” This study found that altered Nrf2 levels may play a significant role in the development of androgenetic alopecia in men.
May 2021 in “F1000Research” This study describes a case series where combining PRP and stromal vascular fraction cells for androgenic alopecia led to denser hair growth and improved hair quality in three patients.
January 2021 in “Medicine Science | International Medical Journal” This study found that men with early androgenetic alopecia had significantly lower total antioxidant capacity compared to healthy age-matched controls.
January 2021 in “Postepy Dermatologii I Alergologii” This study evaluated oxidative stress parameters in patients with androgenetic alopecia but does not report new clinical outcomes.
May 2019 in “Asian Journal of Chemistry” Finasteride forms three new products under acidic stress.
316 citations
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June 2017 in “Stem Cell Research & Therapy” This review covers the potential of SVF and ADSC therapies in regenerative medicine and highlights the challenges of regulation and efficacy, without reporting new clinical results.
248 citations
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December 2011 in “Journal of Neuroscience” This study demonstrated that stress-derived neurosteroid THDOC shifts from inhibiting to activating the HPA axis under stress, presenting potential therapeutic targets for stress-related disorders.
228 citations
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January 1997 in “Birkhäuser Basel eBooks” This article integrates existing literature on hair follicle structure and formation at the cellular and molecular level, reporting no new findings.
204 citations
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February 2000 in “Current Medicinal Chemistry” This review discusses the use of antiandrogens like flutamide and its derivatives in prostate cancer treatment and highlights the need for next-generation antiandrogens for improved efficacy; it reports no new clinical results.
203 citations
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July 2017 in “Biotechnology and Genetic Engineering Reviews” This review discusses the various components essential for successful tissue engineering, such as cell sources, modification methods, and supportive matrices, and highlights the need for functional synergy without reporting new experimental results.
158 citations
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June 2014 in “Journal of Lipid Research” This review summarizes recent discoveries of GPCRs for lysophosphatidylserine and lysophosphatidylinositol, detailing their roles as lipid mediators, but reports no new experimental results.
124 citations
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November 2019 in “International Journal of Molecular Sciences” This review discusses different processing methods for isolating human AD-SVFs/AD-MSCs using various kits and reports no new clinical results, highlighting the need for standardized preparation techniques.
116 citations
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April 2020 in “Stem Cell Research & Therapy” This study identified highly variable genes in mesenchymal stem/stromal cells that are linked to classic functions like development and inflammation response, suggesting their potential as markers for further potency studies.
108 citations
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October 2003 in “Journal of biological chemistry/The Journal of biological chemistry” This study documents that trichohyalin acts as a multi-functional cross-bridging protein in the inner root sheath of mouse hair follicles, enhancing mechanical strength by linking keratin filaments to the cell envelope.
106 citations
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June 1990 in “Journal of Investigative Dermatology”
88 citations
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February 2008 in “Journal of Medicinal Chemistry” Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.
86 citations
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January 1996 in “Clinics in dermatology” This review discusses the effects of protein-based cosmetics on hair properties and reports no new research findings, suggesting potential benefits for developing advanced, sustainable hair products.