Hair can't be as strong as Rapunzel's because it's impractical to scale up due to defects.
This study suggests that the exercise-induced cytokine IL-15 can improve wound healing in aged skin, along with previously reported benefits on skin structure and mitochondrial function.
December 2019 in “C&EN Global Enterprise” This study found that the internal structure and fracture patterns of hair vary among different mammal species, which could inform the development of keratin-based biomaterials for medical and cosmetic applications.
April 2019 in “Digital Library of Theses and Dissertations (Universidade de São Paulo)” This study found that the acidic hair straightening formulation at pH 1.0 improved hair alignments and straightening effectiveness more than pH 2.0, but it weakened fiber strength and affected hair color and composition.
This study found that in vitro, EGCG may help treat colorectal cancer by targeting iron chelation and the ER stress pathway, leading to apoptosis in cancer cells while sparing normal cells.
September 2018 in “Cosmetics” This study found that anisotropic osmolyte solutions may improve hair follicle turnover and condition in both in vitro and in silico models, as well as in human volunteers with hair disorders.
May 2018 in “The Knowledge Bank (The Ohio State University)” In this study, occasional attendance at religious services among adolescents was associated with lower hair cortisol levels, indicating lower chronic physiological stress, compared to regular attendance or none at all.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified a novel mechanism by which dsRNA-induced TLR3 activation and retinoic acid pathways contribute to new hair follicle formation after deep wounds in mice and suggested a similar potential in humans.
September 2017 in “Journal of Investigative Dermatology” Ceramide may help delay hair aging by restoring stressed hair cells.
July 2017 in “Cancer Research” This study found that polyamines participate in DNA double-strand break repair, primarily by enhancing the homologous recombination pathway through RAD51-mediated DNA strand exchange.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests a connection between the unfolded protein response and upregulation of NKG2D ligands in stressed hair follicles, highlighting a potential role of PRDX5 in alopecia areata pathogenesis.
April 2017 in “Journal of Investigative Dermatology” This study found that down-regulation of sonic hedgehog gene expression is a critical early event in chemotherapy-induced tissue damage in hair and feather follicles.
March 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study suggests that using vitamin A, vitamin E, and vitamin C for two months may enable a reduction in corticosteroid dosage for alopecia areata, potentially mitigating associated side effects.
This study found that neonatal administration of Allopregnanolone may mitigate some behavioral effects of early maternal separation in adolescence, but also lead to similar adverse effects as the separation in adulthood.
September 2016 in “Springer eBooks” Gray hair is caused by oxidative stress damaging hair cells.
April 2016 in “Journal of Investigative Dermatology” This study identified mefloquine as a potent inducer of lethal ER stress that effectively eliminated vemurafenib-resistant and sensitive melanoma cells, suggesting its potential for repurposing as a melanoma treatment.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that targeting the tumor stroma to promote the formation of dermal condensates may offer a novel approach to treating basal cell carcinoma.
November 2015 in “Summit (Simon Fraser University)” In this study, significant changes in hair fiber dimensions were observed between pre- and post-operative states in males undergoing abdominal surgery, with values normalizing by the fourth post-operative week.
October 2015 in “Cosmetic Dermatology” This review examines the science and technology behind temporary and permanent hair straightening, discussing the processes, potential advancements, and considerations for reducing adverse effects, but does not report new research findings.
This study found that areola formation in mice requires a combination of pregnancy hormones and mechanical strain, with individual stimuli causing only modest changes in epidermal proliferation and connective tissue remodeling.
March 2015 in “Plastic and reconstructive surgery” This chapter reviews the skin's structure and its clinical relevance, highlighting connective tissue diseases and the potential for novel treatments like protein, cell, or stem cell transfer, but reports no new findings.
This study found that hair cortisol concentrations in mother-daughter pairs are a potential biomarker for cortisol responses to chronic stress, with daughter-mother similarities affected by parenting styles and children's symptoms.
May 2013 in “Journal of the ASEAN Federation of Endocrine Societies” This case study reports that a 61-year-old woman with high testosterone levels due to stromal luteoma of the left ovary experienced rapid normalization of testosterone levels after surgical removal of the tumor.
April 2013 in “The FASEB journal” This study observed that Platycarya strobilacea S. et Z. extract enhanced hair growth and improved hair follicle length and immune response in mice compared to control groups.
January 2013 in “CINECA IRIS Institutial research information system (University of Pisa)” January 2013 in “프로그램북(구 초록집)” This review discusses the chemical processes involved in hair styling and straightening and reports no new results; the authors highlight pregnancy safety with hair treatments during pregnancy.
January 2011 in “Leather Science and Engineering” This study found that rabbit skin histology revealed changes in collagen and elastic fibers after soaking, dehairing, and tanning processes, impacting fiber tightness and fur removal.
June 2010 in “Journal of Chemical Crystallography” This study determined the crystal structure and conformation of synthesized 17x-Acetoxy-pregn-4,6-diene-3,20-dione, revealing specific molecular interactions and structural details in an orthorhombic crystal system.
June 2010 in “Journal of Veterinary Clinics” This study established an experimental model to visualize calcium ion distribution after skin barrier damage in canine epidermis, observing that calcium gradients changed differently depending on the type of damage and time elapsed.
March 2010 in “Cosmetic Dermatology” Hair straightening methods have advanced to improve effectiveness and reduce damage, but still rely on heat and chemicals.