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Some lesser-known causes of PCOS include autoimmune issues, genetic mutations, and changes in the body's microbiome.

Benzothiazepines like diltiazem reduce anxiety in mice by making neurosteroids.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

A patient produced cortisol after adrenalectomy, possibly due to residual tissue or other body parts making steroids.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

COVID-19 may harm male fertility and damage the reproductive system.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Stress can worsen skin conditions by affecting hormone levels and immune response.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

PCOS is a long-term condition that needs more research for better understanding and treatment.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.

Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.

Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.

Neurosteroids show promise for treating epilepsy and more research is needed.

Toxoplasma gondii infection may increase testosterone levels in males.

Finasteride blocks progesterone's effect on absence seizures in rats.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.

Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.