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Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

Wnt4 protein makes the outer skin layer thicker in burn wounds by turning on a specific healing pathway and loosening the connections between skin cells.

Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.

Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Some skin diseases and their treatments can negatively affect male fertility.

PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

Adrenal disorders can cause lasting brain and behavior issues in children.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.

The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.

Stress-related hair loss was reversed with a special medication.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

Early NAS level changes affect alcohol consumption vulnerability.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.

Muscles can make their own androgens, which may help muscle growth.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.