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The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.

Chemicals from the plant Dicerocaryum senecioides were found to safely speed up and increase hair growth in mice.

Analog 23 is a promising compound for prostate cancer treatment.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.

Adiantum capillus extract reduces pain and swelling in animals.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Plant cell culture is a promising method for creating sustainable and high-quality cosmetic ingredients.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Cuscuta reflexa extract may help treat hair loss caused by hormones.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

Suppressing certain hormones might help prevent prostate cancer.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Mutations in certain receptors can cause diseases and offer new treatment options.

Ganoderma lucidum may help treat enlarged prostate in rats.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Liposomes can make the antiandrogen RU 58841 more effective for skin application by reducing absorption, increasing skin retention, and targeting sebaceous structures.

Asiasari radix extract may relieve certain types of pain by affecting GABA and NMDA receptors.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.