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This review discusses strategies for treating hormone-dependent prostate diseases and synthesizes a range of potential 5α-reductase inhibitors, but experimental evaluation of these compounds was not completed.

In this study, researchers examined 1,000 South Asian patients misusing topical corticosteroids for dermatophytosis and found that this misuse resulted in atypical, chronic, and recurrent fungal infections called steroid-modified dermatophytosis, often involving extensive and atypical skin presentations.

This study reports that 2-(1-Adamantyl)-4H-thiochromen-4-on-6-O-sulfamate is the most potent steroid sulfatase inhibitor identified so far, exhibiting 170-fold higher activity than the lead compound estrone sulfamate.

This study found that Atlantic croaker nuclear androgen receptors AR1 and AR2 have different binding affinities for androgens, suggesting that they may mediate distinct physiological actions in teleosts.

This case study highlights how trichoscopy helped differentiate between diffuse alopecia areata and trichotillomania in an 11-year-old girl, demonstrating its importance in distinguishing hair disorders with similar presentations.

This study constructed a model to predict finasteride's inhibitory activity on 5α-reductase type 2 and calculated that a 1 μM plasma concentration, after 50 mg administration, matches prostate inhibition levels.

This case study describes a cat with concurrent cutaneous xanthomas, demodicosis, and dermatophytosis, which suggests potential primary hyperlipidaemia as the underlying cause for its symptoms.

The document explains various skin conditions in cats and how to diagnose and treat them.

This article reviews common scalp and hair disorders in children and adolescents and outlines diagnostic approaches, but reports no new clinical findings.

The document concludes that scalp disorders can be treated with hair washing, specific shampoos, medications, and sometimes surgery or hair transplants, but hereditary baldness is untreatable.

This article discusses the uses and techniques of trichoscopy for hair and scalp disorders and reports no new clinical results.

This case report identifies a 13-year-old boy with disseminated tinea incognito, emphasizing the importance of considering fungal infections when red and scaly lesions persist despite corticosteroid treatment.

This case report describes an 18-month-old boy who developed a rare phototoxic skin reaction to terbinafine, likely triggered by sunlight exposure, which resolved after treatment with corticosteroid cream and sun avoidance.

This case report describes a 52-year-old woman with erythema annulare centrifugum after using topical luliconazole and oral itraconazole, suggesting a drug-induced reaction confirmed by a positive rechallenge test.

This review discusses various causes and treatments of scalp pruritus, distinguishing between conditions with primary skin lesions and those without, but provides no new clinical results.

Different types of alopecia in children require specific diagnoses and treatments.

This review discusses treatment options for tinea capitis in children and reports no new clinical results; the authors recommend newer antifungal agents in cases of griseofulvin treatment failure.

This case report describes a 5-year-old girl with an extensive Microsporum canis scalp infection, highlighting griseofulvin as the preferred treatment and noting corticosteroids' benefit in severe inflammatory cases.

In this study, researchers analyzed data from 132 hospitalized kerion patients over 11 years, mostly children under 11 from rural areas, and noted a significant male predominance and frequent animal contact as potential transmission factors.

This review provides a detailed overview of the causes, prevalence, pathophysiology, clinical presentation, and treatment of beard alopecia, highlighting conditions such as alopecia areata, pseudofolliculitis barbae, and tinea barbae, and aims to serve as a resource for clinicians handling such cases.

The document concludes that scientists created various steroids with different properties, including a more effective semi-synthetic vitamin D.

This study identified novel compounds as selective inhibitors of the type 1 isoenzyme of 5α-reductase, displaying promising potential for treating DHT-dependent disorders such as acne and androgenic alopecia.

This research article focuses on nonsteroidal inhibitors of human type I steroid 5-alpha-reductase but reports no new results.

This study developed a new synthetic route for finasteride that omits the costly reagent 2,2′ dipyridyl disulfide, achieving an overall yield of 16%.

This study found that manipulating AKR1D1 expression in human liver cells effectively regulates glucocorticoid clearance and receptor activation, highlighting its role in liver-specific steroid hormone regulation.

This study found that specific steroids, particularly 5 and 7b, decreased growth of prostate and seminal vesicles and bound to the androgen receptor, showing comparable pharmacological activity to finasteride.

This research investigated the design and synthesis of steroid-based compounds as aromatase inhibitors for breast cancer, finding that certain structural modifications significantly enhance their inhibitory potency.

This review focuses on coumarin analogs with potential antibreast cancer activities but reports no new clinical results, highlighting their mechanisms of action and structure-activity relationships.

This article discusses the various roles of steroids in vertebrate organ systems and notes several glucocorticoids that were among the Top 200 Drugs by sales in the 2010s, but it reports no new clinical findings.

This review examines the role of cyclodextrins in improving the solubility, stability, and bioavailability of steroid drugs but does not report new experimental findings.