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Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

The T-zone on the face has more androgen receptors and produces more oil than the U-zone.

A new compound effectively inhibits human 5α-reductase 1.

Giving dihydrotachysterol to mother rats caused skin hardening and bone issues in their babies through milk.

Dogs with sex hormone imbalances may not drink or pee a lot but often lose hair on their body and can have reproductive system issues.

Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

A woman's severe hormone imbalance after menopause led to finding a rare ovarian tumor, treated by surgery.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

Testosterone increases muscle mass regardless of DHT conversion blocking.

Hair cortisol levels can show increased stress during late pregnancy but only for up to six months.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.

Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.

Four-amino acid part makes enzyme sensitive to finasteride.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Most dogs with alopecia had higher than normal levels of certain hormones, but hair loss might not always be linked to these hormone changes.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.

Dutasteride is more efficient than finasteride, but individual results vary.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.