research Role of Androgen on Physiological Function of Pilosebaceous Unit
Androgens like testosterone affect oil production and hair growth in skin and hair follicles.
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research Role of Androgen on Physiological Function of Pilosebaceous Unit
Androgen affects oil production and hair growth in the skin.
research Defects in Androgen Biosynthesis Causing 46,XY Disorders of Sexual Development
Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.
research Studies on the Persistence of Estradiol Benzoate and Nortestosterone Decanoate in Hair of Cattle Following Treatment with Growth Promoters, Determined by Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry
Detecting steroid esters in cattle hair is inconsistent and influenced by sampling factors.
research Neurosteroids Are Endogenous Neuroprotectants in an Ex Vivo Glaucoma Model
A natural steroid in the body may protect against eye damage in glaucoma.
research Brain Allopregnanolone Induces Marked Scratching Behavior in Diet-Induced Atopic Dermatitis Mouse Model
A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.
research Sex Hormones and Acne: The Role of the Skin as an Endocrine Organ
Sex hormones, especially androgens, play a key role in causing acne.
research Potential Adverse Effects of Long-Term Testosterone Therapy
Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.
research Which Chemicals Should Be Grouped Together for Mixture Risk Assessments of Male Reproductive Disorders?
Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.
research In Vitro and In Vivo Regulation of SRD5A mRNA Expression of Supercritical Carbon Dioxide Extract from Asparagus Racemosus Root as Anti-Sebum and Pore-Minimizing Active Ingredients
Asparagus racemosus root extract reduced sebum and pore size in men but not in women.
research Testosterone Hormone: Clinical Indications, Dysregulation, and Therapeutic Methods
Testosterone is vital for male health, and its deficiency is linked to aging and common health issues.
research Steroidogenesis Inhibitors Alter But Do Not Eliminate Androgen Synthesis Mechanisms During Progression to Castration-Resistance in LNCaP Prostate Xenografts
Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.
research Androgen Receptors and Androgen-Dependent Initiation of Protein Synthesis in the Prostate
Prostate cells have proteins that bind to specific hormones, which can increase protein production when activated by these hormones.
research Acne in Dark Skin: Prevalence, Presentation, and Treatment
Acne in dark skin is influenced by environmental factors and can lead to hyperpigmentation, with various treatment options available.
research Testosterone Metabolite Nonessential For Androgen Effects
The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.
research Tuberculosis Mimicking the Onset of Systemic Lupus Erythematosus Flare: Case-Based Review
TB can mimic SLE symptoms, so doctors should consider TB in such cases.
research Spironolactone Therapy for Hirsutism in a Hyperandrogenic Woman
Spironolactone may help reduce excessive hair growth in women with high male hormone levels.
research Thyroid Hormones and Androgens Differentially Regulate Gene Expression in Testes and Ovaries of Sexually Mature Silurana Tropicalis
Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.
research Use of Spironolactone in Dermatology
Spironolactone is used in dermatology to treat skin conditions related to hormones, but is not safe for pregnant women or men.
research Alopecia Areata in Aging C3H/HeJ Mice
Alopecia areata in these mice is inherited, more common in young females, and can be treated with triamcinolone acetonide.
research Cyclic Cushing Syndrome Caused By An ACTH-Producing Pheochromocytoma
A woman's cyclic Cushing syndrome was caused by a tumor in her adrenal gland that produced ACTH.
research Genetics and Pathophysiology of Congenital Adrenal Hyperplasia
The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.
research Urticaria, Drug Hypersensitivity Rashes, Nodules and Tumors, and Atrophic Diseases
The document concludes that various skin conditions have specific treatments, ranging from antihistamines for urticaria to surgery and medication for tumors and chronic skin diseases.
research Androgen Metabolism in Hirsute Patients Treated with Cyproterone Acetate
Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.
research Androgen Treatment of Postmenopausal Women
Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.
research The Effect of the Antiandrogen 11α-Hydroxyprogesterone on Sebum Production and Cholesterol Concentration of Sebum
The antiandrogen 11α-hydroxyprogesterone effectively reduces skin oil and cholesterol when applied to the skin.
research LY191704: A Selective, Nonsteroidal Inhibitor of Human Steroid 5 Alpha-Reductase Type 1
LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
research Overexpression of Aldo-Keto Reductase 1C3 in LNCaP Cells Diverts Androgen Metabolism Towards Testosterone Resulting in Resistance to the 5α-Reductase Inhibitor Finasteride
Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.
research In Vivo Time-Dependent Inhibition of Human Steroid 5α-Reductase by Finasteride
Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.
research Consequences of Steroid-5α-Reductase Deficiency and Inhibition in Vertebrates
Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.