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The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Spironolactone most effective for hirsutism, but has side effects.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

Gilles de la Tourette syndrome is treatable, with behavioral therapy as a recommended first option and other treatments available for more severe cases.

Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.

Early treatment of acne is important to prevent scarring and improve appearance, using medications that can have side effects.

A rare benign skin tumor showed unusual features of sebaceous and sweat glands, important for correct diagnosis.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Finasteride reduces prostate cancer risk but may increase high-grade cancer chances.

Different human traits like skin color and hair type vary between populations due to genetic adaptations to the environment.

Genetic mutations can affect female sexual development, requiring personalized medical care.

Ashwagandha root improved symptoms of nonclassic 11-hydroxylase deficiency in an elderly woman.

Ashwagandha may improve hormone levels and reduce hair loss in non-classical adrenal hyperplasia.

The link between physical signs of high male hormones and hormone levels in women with PCOS changes with age.

Testosterone is key for male sexual function, and treating hormone imbalances can improve sexual issues.

Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.

Ovarian vein sampling helped diagnose rare ovarian tumors causing high testosterone, and surgery to remove the tumors lowered the testosterone levels.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

DHT, a testosterone byproduct, causes male pattern baldness.

Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

Finasteride may affect fetal brain development and increase arousal, but more research is needed for safety confirmation.

Finasteride blocks progesterone's effect on absence seizures in rats.

Dutasteride makes alcohol less sedating and may lead to less drinking in men.