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Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.

Acne keloidalis nuchae is a tough-to-treat condition that greatly affects quality of life, especially in men of African descent.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

LCN may improve finasteride delivery for hair loss treatment.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Different hair care practices and conditions affect African American hair and scalp health, requiring specialized knowledge for treatment.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Chitosan-decorated polymersomes improve finasteride delivery for hair loss treatment.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

The document explains hair growth and shedding, factors affecting it, and methods to evaluate hair loss, emphasizing the importance of skin biopsy for diagnosis.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

The method effectively detects banned substances in urine for sports antidoping.

Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.

These skin conditions in African men need combined medical treatments and lifestyle changes.

The document concludes that more research is needed to understand how to treat muscle pain with drugs.

Possible new treatments for common hair loss include drugs, stem cells, and improved transplants.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Jojoba oil is highly valued for its diverse medicinal and industrial uses.

Androgens significantly affect female hair loss, and hormonal treatments may help.

Melatonin improves cashmere goat hair growth and quality by increasing antioxidants and reducing cell death.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.

New compounds with carborane showed anti-androgen effects similar to flutamide.

The conclusion is that fat grafting is safe and effective but carries risks that need careful management.