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This study found that the anti-apoptotic Bcl-2 protein plays a crucial role in maintaining hair follicle stem cell function and influences tissue regeneration and tumor formation in mice.

This study found that conditioned media from human amniotic fluid-derived stem cells may enhance skin regeneration by promoting cell proliferation and migration, and by modulating gene expressions altered by UV irradiation.

This review discusses current stem cell technologies, their potential therapeutic uses, and imaging techniques for tracking transplanted cells, without reporting new experimental results.

This review discusses the molecular mechanisms driving hair follicle degeneration in skin aging and emphasizes the role of the tissue microenvironment on stem cell function, but reports no new research findings.

Tanshinone IIA helps protect tissue from low oxygen damage by activating certain cell pathways.

This case report describes a 22-year-old woman who developed persistent, non-scarring hair loss and premature ovarian failure following a myeloablative umbilical cord transplant for acute myeloid leukemia.

This case report describes a patient with permanent chemotherapy-induced alopecia who experienced full hair regrowth after treatment with low-dose oral minoxidil.

This review explores the potential role of caveolin-1 in cicatricial alopecia, particularly frontal fibrosing alopecia, and discusses possibilities for targeted therapies without providing new research results.

This study established that the Dct::CreERT2 mouse line is effective for targeting and studying adult melanocyte stem cells, contributing to the understanding of melanocyte biology and hair pigmentation.

This study found that hair follicle stem cells in the hairpoor mouse, a model for Marie-Unna hypotrichosis, lose their quiescent state, leading to a disordered hair cycle and contributing to alopecia.

This article provides industry updates on stem cell research and regenerative medicine from December 2019 and reports no new research findings.

This review discusses transplantation of melanocyte stem cells for vitiligo treatment and reports no new clinical results; it suggests the procedure could be effective in reactivating melanocyte precursors for repigmentation.

This research observed that translation initiation shifts from cap-dependent to IRES-mediated pathways varied across tissues and cell types under stress and differentiation conditions in mice, with low IRES/Cap ratios signaling high stemness and potential multipotency, mediated by the RNA processing protein PTBP1.

This study investigated the secretome of adipose mesenchymal stem cells and fibroblasts used in skin care products, finding 16 therapeutic pathways involving numerous signaling mechanisms, which may offer skin benefits through anti-inflammatory and regenerative effects.

This review reports that transcriptional and epigenetic mechanisms in epithelial stem cells guide their fate in the epidermis and hair follicles, crucial for skin homeostasis, but disruptions can lead to disease.

In this study, the authors explored the role of Lgr5+ hair follicle stem cells and their regulation through the Wnt/-catenin pathway, highlighting how precise modulation of this pathway is crucial for treating hair loss safely and effectively.

This review summarizes the potential therapeutic applications of stem cells in dermatology, emphasizing their role in restorative and regenerative treatments through injections, topical applications, and scaffolds, supported by advancements in laboratory processes and quality control.

This study found that ING5 knockout mice are prone to developing lymphomas and severe dermatitis, suggesting ING5 plays a role in tumor suppression and stem cell maintenance in vivo.

This review outlines the current state of stem cell therapy in dermatology, highlighting its potential for treating a variety of skin disorders and conditions, while emphasizing the need for further controlled studies to standardize treatment and fully understand its efficacy and limitations.

This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.

This review examines the potential of stem cells and their derived products, such as exosomes and conditioned media, in improving burn wound healing but presents no new clinical data.

This chapter reviews the presence and roles of stem cells in various body systems, focusing on their lifelong function in animals and humans, and reports no new experimental findings.

This review examines mesenchymal stem cell therapy as a promising alternative for end-stage liver disease, discussing completed clinical trials and highlighting challenges that must be addressed before clinical application.

This study found that Myc activation in mouse epidermis impairs keratinocyte adhesion and motility by downregulating extracellular matrix and cytoskeleton proteins, affecting hair lineage differentiation.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

This review discusses the diverse roles and characteristics of epidermal and dermal stem cells in skin regeneration and aging, highlighting their potential applications in regenerative medicine and reports no new clinical results.

This review explores how adipose-derived stem cells contribute to skin homeostasis and highlights recent advances in their clinical applications in dermatology, but it reports no new clinical results.

This study suggests that while VDR is crucial for maintaining hair follicles in mice, their degeneration may be linked to impaired cell migration during hair growth phases rather than stem cell loss.

This review discusses how inflammation influences hair follicle stem cell activities like wound healing and follicle cycling and suggests a potential link between inflammation, stem cell activation, and programmed cell death.

This perspective discusses Villani et al.'s findings on the role of the IGF regulatory protein Igfbp2 in basal cell carcinogenesis and highlights potential therapeutic and preventive targets, while raising questions about the cell of origin.