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This study reports that human adipose-derived stem cells cultured with platelet lysate instead of fetal bovine serum demonstrate enhanced stress resistance, reduced cellular aging, and faster wound healing in mice, due in part to upregulated stress response and proliferation genes.

This case study reports that reducing scalp massage following minoxidil application and using mesenchymal stem cell exosomes led to significant improvement in hair condition for a patient with trichorrhexis nodosa.

This review suggests that melatonin may increase hair density and reduce hair shedding, but variations in study designs highlight the need for more standardized clinical trials.

This study found that toll-like receptor 9 plays a previously unrecognized role in sensing skin injury and influencing tissue repair and regeneration in adult mice by modulating γδT cell migration.

This chapter reviews therapies for skin and corneal regeneration and hair loss, discussing various treatments but presenting no new research findings.

In this study on C57BL/6 mice, researchers found that cadmium chloride exposure led to metabolic disruption, accelerated skin aging, and impaired hair regeneration, with more severe effects observed at higher doses.

Linalool in fragrances may harm hair follicles and contribute to hair loss.

This article presents Stemson Therapeutics' development of a stem cell-based approach to generate new hair follicles for treating hair loss, which remains in preclinical stages without tested human results.

This article discusses the role and potential of plant stem cell extracts in cosmetics for their antioxidant and protective effects on skin cells, reporting no new clinical results; the authors highlight ecological and sustainable production methods.

This study found that basal lower proximal cup cells in mice are key to regenerating hair follicles after chemotherapy-induced damage, while traditional bulge stem cells remain inactive.

This study found that human skin melanocytes with low mutation burdens are smaller, less dendritic, and exhibit stem-like features, often residing in UV-protected hair follicles, suggesting their role in replenishing sun-damaged epidermis.

This review highlights the potential of cell-free therapies, particularly cell extracts, in addressing radiation-induced salivary gland damage from head and neck cancer treatment, emphasizing their practicality and safety compared to traditional therapies despite incomplete understanding of their bioactive components.

This study found that COVID-19 infection disrupts spermatogenesis, alters testicular cell populations, and may impact male fertility by causing long-term changes in testicular function and reduced sperm quality, as observed even in patients who have recovered from the acute phase of the infection.

This research found that Foxc1 promotes quiescence in hair follicle stem cells and identified COL17A1 depletion, due to DNA damage, as a cause of hair thinning and loss during aging.

This study found that spironolactone enhanced the effectiveness of non-DNA-damaging cancer drugs gemcitabine and osimertinib in cancer cell lines and a mouse xenograft model, likely by suppressing the anti-apoptotic protein survivin.

This study found that stem cell transplantation effectively reduced acute inflammation-induced testicular damage, suggesting potential for cell-based therapies in addressing male infertility.

This study found that acute stress can cause rapid hair loss by triggering necrosis in hair follicle cells and initiating autoimmunity, revealing a mechanism where stress-induced nerve activity leads to tissue damage and immune system activation.

This study found that after injury, the bone marrow microenvironment's increased Wnt10b expression supports hematopoietic stem cell regeneration by enhancing Wnt signaling, revealing a vital interaction during recovery.

In this study, researchers found that hair follicle-derived mesenchymal stem cells, modified to overexpress extracellular matrix protein 1, significantly improved liver function and reduced liver damage in cirrhotic mice by inhibiting hepatic stellate cell activation and TGF-β/Smad signaling.

This review highlights exosomes as a promising treatment for skin damage from UV light, infrared radiation, burns, and disorders due to their anti-inflammatory properties, ability to induce macrophage polarization, and acceleration of skin repair and regeneration.

This review discusses the potential of adipose-derived stem cells for regenerative medicine, highlighting their ability to differentiate, secrete factors, and modulate the immune response, but reports no new findings.

This review discusses the plasticity of epithelial stem cells in regenerative contexts and reports no new research findings; the authors highlight potential implications for regenerative medicine and cancer.

This study found that topical ruxolitinib protected Lgr5+ skin stem cells and maintained skin homeostasis in skin GVHD, unlike corticosteroids.

In this study, finasteride was shown to inhibit glioma stem-like cells and reduce glioblastoma proliferation, suggesting its potential as an anti-glioblastoma drug.

This review discusses the use of umbilical cord blood in regenerative medicine, focusing on collection, banking processes, and ethical considerations, without presenting new clinical results.

This review discusses the use of mesenchymal stem cells in treating diseases, particularly focusing on their application in pediatric Graft-versus-Host Disease, with most studies reporting safety and effectiveness in animals.

This study reports that human epidermal neural crest stem cells from hair follicles can be quickly differentiated into highly pure human Schwann cells without genetic manipulation, suggesting their potential for therapeutic applications.

The study suggests that immune privilege collapse in bulge cells and the involvement of pro-inflammatory cytokine interferon-γ contribute to hair follicle stem cell loss in lichen planopilaris.

In this study, researchers observed that platelet-rich plasma-derived exosomes significantly promoted hair regeneration in a murine model of alopecia by enhancing hair follicle stem cell activities and modulating the SIRT1/FoxO3a pathway, suggesting potential clinical benefits for alopecia treatment.

This study found that human umbilical cord blood-derived mesenchymal stem cells (HUCB-MSCs) improved hair growth and follicle structure in male rats with androgenic alopecia, achieving better results and longer-lasting effects compared to minoxidil treatment, with no observed side effects.