February 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this study, all-trans retinoic acid was found to protect against oxidative stress-induced apoptosis in cultured hair cell-like cells.
13 citations
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November 2024 in “Frontiers in Microbiology” This review assessed the potential of mesenchymal stem cell therapy to enhance burn wound healing, highlighting its capabilities in promoting angiogenesis, reducing inflammation, and regenerating damaged tissues, while identifying preclinical and clinical challenges that need addressing to optimize treatment outcomes.
May 2020 in “Research Square (Research Square)” In this rat study, bone marrow mesenchymal stem cell therapy reduced mortality and intestinal damage in acute liver failure by alleviating endotoxemia.
April 2019 in “Journal of Investigative Dermatology” Targeting immune pathways like JAK/STAT may help treat frontal fibrosing alopecia.
In this study, preconditioning hair follicle-derived stem cells with valproic acid and/or rapamycin was shown to protect against damage caused by oxygen glucose and serum deprivation, potentially enhancing stem cell therapy efficacy for ischemic stroke by improving cell adaptation to oxidative stress.
508 citations
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February 2007 in “Cell” This article reviews the biology of epithelial stem cells and their role in tissue self-renewal, maintenance, and regeneration, and it highlights the clinical implications of understanding their signaling pathways, but it presents no new clinical findings.
Intermittent fasting slows hair growth by damaging hair follicle cells.
April 2015 in “Plastic and Reconstructive Surgery” This article is from the ASPS Education Network and does not report any new research findings.
April 2015 in “Plastic and Reconstructive Surgery” This article discusses the role of the American Society of Plastic Surgeons in plastic and reconstructive surgery education but presents no new research findings.
1 citations
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November 2023 in “Dermatological Reviews” This review highlights advancements in skincare aimed at addressing the effects of aging and environmental factors, including new techniques to rejuvenate skin cells and reduce inflammation, though challenges like complex routines and costs limit widespread adoption.
August 2019 in “Journal of Medical Histology” This review discusses the role of epithelial mesenchymal transition (EMT) in wound healing and tissue repair, highlighting its potential contributions to progenitor cell pools, but reports no new clinical findings.
September 2025 in “Journal of Zhejiang University (Medical Sciences)” This review highlights how peripheral nerves play key roles in skin wound healing by modulating immune responses, regulating stem cell functions, and promoting vascularization, suggesting potential avenues for therapeutic strategies targeting neuroregulation.
1 citations
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January 2023 in “Science Advances” This study found that bacterially induced metabolic changes in stem cells can enhance skin and hair follicle regeneration in both mice and humans, suggesting potential strategies for improving recovery after injury.
July 2022 in “Journal of Investigative Dermatology” This study identified that bacterially-induced metabolic changes in keratinocytes enhance skin and hair follicle regeneration, suggesting that modifying skin microbiome interactions may improve wound healing.
218 citations
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April 2008 in “Genes & Development” This research discusses how epithelial stem cells in the skin maintain normal homeostasis, contribute to wound repair, and highlights the importance of these processes, as defects can lead to skin diseases including cancers, but provides no new experimental results.
60 citations
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December 2020 in “Stem Cell Research & Therapy” In this laboratory study, ASC-conditioned medium showed higher therapeutic potential than extracellular vesicles alone in reducing inflammation and catabolic activity in human chondrocytes with an osteoarthritis phenotype, highlighting its possible use in osteoarthritis management.
18 citations
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October 2020 in “Radiation Research” This review discusses the similarities between COVID-19 and acute radiation syndrome, highlighting their shared inflammatory responses and suggesting that insights from radiation biology could inform COVID-19 research and treatment approaches; it reports no new clinical results.
13 citations
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March 2018 in “Journal of Sociology” This article argues that the promissory discourse in the anti-ageing treatments market exploits societal anxieties about ageing, but its long-term sustainability is questionable as many promises remain undeliverable.
13 citations
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January 2010 in “Advances in Biochemical Engineering / Biotechnology” This review covers various aspects of hair biology, pigmentation, and development, focusing on genetic and biochemical modulation of hair follicle components but reports no new findings.
1 citations
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January 2021 in “Journal of Cancer Therapy” This article reviews regenerative medicine strategies, such as stem cells and plant polyphenols, for mitigating radiotherapy side effects but does not present new clinical findings, calling for further investigation.
1 citations
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October 2013 in “The Journal of Dermatology” This letter to the editor discusses the immune response related to hair loss in a case of atypical drug-induced hypersensitivity syndrome but reports no new research findings.
This study used an ex vivo human skin model to show that tropical conditions disrupt skin homeostasis, resulting in epidermal thickening and junctional flattening, and found that Kombucha tea extract may help preserve skin structure under such stress.
This review discusses the role of stem cells in the hair follicle bulge region for regenerative medicine and reports no new clinical results; the authors highlight the complexities in studying these cells' involvement in alopecia.
November 2013 in “Journal of clinical & experimental dermatology research” This narrative review discusses the potential of urinary bladder matrix as a bio-scaffold in hair restoration but provides no new clinical results or trials; it highlights regenerative technology and suggests further exploration.
2 citations
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June 2001 in “American Journal of Pathology” This article explores the complexity and significance of the hair follicle, emphasizing new insights into its biological roles and the involvement of p53 in follicular regression.
1 citations
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January 2019 in “Journal of Embryology & Stem Cell Research” This review discusses mesenchymal stem cells' role in tissue regeneration and skin anti-aging, highlighting their migration to damaged sites and secretome effects, but reports no new clinical results.
4 citations
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April 2002 in “Medical Hypotheses” Hormones cause hair loss by affecting cell growth and weakening cell attraction.
3 citations
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January 2021 in “Oxidative Medicine and Cellular Longevity” In this study, Nrf-2-expressing hair follicle mesenchymal stem cells showed the most significant therapeutic effect in a rat model of ulcerative colitis, suggesting a new potential treatment for the disease.
26 citations
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January 2018 in “Annals of dermatology/Annals of Dermatology” This review examines current understanding of hair graying and suggests it may be caused by depletion of melanocyte stem cells due to genotoxic stress or dysfunctional melanocytes from oxidative stress.
6 citations
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October 2022 in “Frontiers in Cell and Developmental Biology” This study suggests that hair follicle mesenchymal stem cells may alleviate small intestinal ischemia-reperfusion injury in rats by promoting angiogenesis, reducing apoptosis, and enhancing intestinal stem cell expression.