April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study demonstrated that prevascularized human skin constructs containing engineered hair follicles can successfully induce human hair growth when grafted onto mice by promoting blood supply to the grafted skin.
September 2016 in “Journal of Dermatological Science” This study investigated the effects of Wnt-3a, Wnt-5a, Wnt11, and Wnt-10b on the hair induction-ability of cultured dermal papilla cells.
December 2015 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found that estrogen treatment induced premature catagen and apoptosis in hair follicles of wild-type mice, while having no effect on mice lacking estrogen receptor α.
January 2014 in “Journal of Tissue Engineering and Reconstructive Surgery” This study found that rabbit hair follicle stem cells, combined with electro-spun nano silk fibers, successfully constructed a tissue-engineered urethra, suggesting potential for future in vivo repair studies.
This study found that putative hair follicle stem cells can successfully be cultured from the bulge area of hair follicles for up to four days, suggesting potential for further development of culture techniques.
April 2012 in “Informa Healthcare eBooks” Lichen planopilaris is a rare, chronic condition causing hair loss, mainly in middle-aged women, and early treatment is important to prevent permanent baldness.
March 2007 in “International Society of Hair Restoration Surgery” This study found that caffeine stimulated hair follicle growth in an ex vivo model of androgenetic alopecia, counteracting testosterone-induced suppression in male patient samples.
January 1963 in “Stain technology” This study describes a staining technique that differentiates medullary from cortical keratin in sheep and goat hair using Ziehl-Neelsen's carbol-fuchsin in skin biopsy sections.
9 citations
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August 1980 in “Journal of Cutaneous Pathology” This study found that Rhodamin B staining of keratin was inconsistent across normal skin, epithelial tumors, and dermatoses, with notable differences in staining intensity between tricho-hyalin and keratohyalin granules.
November 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, researchers conducted additional IHC staining on equine skin sections and found that collagen type III primarily labels the extracellular matrix, while anti-PDGFR-antibody staining highlights cells with long-shaped processes mainly arranged around hair follicles.
71 citations
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February 1992 in “Journal of Cutaneous Pathology” This study found that monoclonal antibodies identified distinct staining patterns in benign and malignant skin appendage tumors, highlighting their potential as markers for analyzing skin tumors.
13 citations
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June 2011 in “International Journal of Dermatology” This study found that a new lecithinized coal tar formulation did not stain different types of mammalian hair, suggesting it may be promising for treating scalp psoriasis without the drawback of staining.
July 2019 in “Indian dermatology online journal” This case report highlights an unusual trichoscopic appearance in alopecia areata due to dithranol staining, which may obscure typical patterns and reveal atypical vascular features in the interfollicular spaces.
32 citations
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February 2002 in “Veterinary Dermatology” This study reported that canine dermal papilla cells showed a distinct growth pattern and strong collagen IV and laminin staining compared to dermal fibroblasts.
6 citations
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January 1985 in “ACTA HISTOCHEMICA ET CYTOCHEMICA” This study found that epithelial components of calcifying epithelioma of Malherbe showed lectin binding and keratin staining patterns similar to normal hair follicles, with prominent Con A staining in tumor giant cells.
3 citations
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December 2024 in “Stem Cell Reports” In this study, researchers observed that low levels of fucose-binding lectin staining characterize limbal epithelial progenitor cells, which maintain a high proliferative capacity and may be enhanced by inhibiting fucosylation, offering insights for regenerative therapy of the limbal stem cell niche.
1 citations
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November 2002 in “Journal of dermatology” This study investigated the histogenetic relationship between basal cell carcinoma and hair follicles, revealing specific staining patterns of a monoclonal antibody in different skin tissues.
32 citations
,
March 2018 in “Neoplasia” This study suggests that nephronectin (NPNT) could serve as a novel prognostic marker for poor prognosis in a subgroup of breast cancer patients, associated with specific NPNT staining patterns.
21 citations
,
March 2018 in “Experimental Dermatology” This practical guide introduces methods to study human dermal white adipose tissue but does not report new clinical results, emphasizing available techniques and staining protocols.
20 citations
,
July 2006 in “Veterinary dermatology” This study found that hair regrowth in Pomeranians with hair cycle arrest treated with melatonin was not associated with a change in oestrogen receptor-α staining.
19 citations
,
July 1994 in “International Journal of Dermatology” This case report describes a 9-year-old Korean boy with a calcified nodule on his earlobe, confirmed by histopathologic examination and Von Kossa staining.
16 citations
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October 2014 in “Oral surgery, oral medicine, oral pathology and oral radiology” This study found that keratoacanthoma of the lip likely arises from outer root sheath cells, based on the presence of specific keratin markers and periodic acid-Schiff staining patterns.
9 citations
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May 2022 in “Actas Dermo-Sifiliográficas” This study found that basal cell carcinoma exhibits altered expression patterns of CD10, p63, BCL-2, and EMA proteins compared to normal skin, with notable differences in staining and reactivity.
9 citations
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January 1992 in “Journal of Investigative Dermatology” This study found distinct differences in UEA I glycoprotein binding on follicular keratinocytes between anagen and telogen hair follicles, with staining associated with follicle length and regrowth.
7 citations
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June 2009 in “Journal of the European Academy of Dermatology and Venereology” This study found that in lichen planopilaris, the basement membrane zone of the hair follicles exhibited disrupted and discontinuous staining patterns, potentially contributing to scarring and irreversible hair loss.
5 citations
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September 2021 in “Journal of Molecular Histology” In this study, the researchers identified LHX2 as a specific marker for hair follicle placodes, differentiating them from eccrine sweat gland placodes through double immunofluorescence staining.
June 2015 in “The American journal of dermatopathology/American journal of dermatopathology” This study demonstrated that a 1-step, peroxidase-labeled conjugated antibody method provides more accurate immunoreactivity patterns in hair follicle substructures compared to the 2-step LSAB method, which may cause false-positive staining in sebaceous glands.
January 2010 in “Seoul National University Open Repository (Seoul National University)” This study investigated vitamin D receptor expression in normal hair follicles and those affected by alopecia areata, focusing on various markers using immunohistochemical staining.
January 2006 in “Zhongguo bijiao yixue zazhi” This study demonstrated a simple and efficient method to isolate epithelial cells from rat vibrissa follicles, reducing labor and contamination risk while maintaining positive K19 staining.
109 citations
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April 1997 in “Archives of Dermatological Research” The researchers reported that mast cell and nerve fiber interactions in mouse skin are highly selective for nerve fiber types and vary depending on the hair cycle phase.