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    Glossary Squalene

    natural compound in sebum, precursor to cholesterol

    Squalene is a natural organic compound that is a precursor to cholesterol and other steroids. It is found in high concentrations in shark liver oil, but also occurs in olive oil, wheat germ oil, and the human sebum. Squalene is valued for its moisturizing properties and is often used in skincare products to help maintain skin hydration and barrier function.

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    Research 30 of 357

    1. Squalene-Containing Nanostructured Lipid Carriers Promote Percutaneous Absorption and Hair Follicle Targeting of Diphencyprone for Treating Alopecia Areata Pharmaceutical Research · 2012 · 59 citations
    2. Tofacitinib Loaded Squalenyl Nanoparticles for Targeted Follicular Delivery in Inflammatory Skin Diseases Pharmaceutics · 2020 · 15 citations
    3. Quantification of Squalene and Lactic Acid in Hair Bulbs with Damaged Sheaths: Are They Metabolic Wastes in Alopecia? Biomedicines · 2023
    4. Surface Lipids as Multifunctional Mediators of Skin Responses to Environmental Stimuli Mediators of Inflammation · 2010 · 105 citations
    5. TREM2 macrophages induced by human lipids drive inflammation in acne lesions Science Immunology · 2022 · 62 citations
    6. Squarticles as a Lipid Nanocarrier for Delivering Diphencyprone and Minoxidil to Hair Follicles and Human Dermal Papilla Cells Aaps Journal · 2013 · 62 citations
    7. Recent studies on the delivery of hydrophilic drugs in nanoparticulate systems Journal of Drug Delivery Science and Technology · 2015 · 47 citations
    8. Characterization of the lipid composition at the proximal root regions of human hair International Journal of Cosmetic Science · 2005 · 41 citations
    9. Prevention of lipid loss from hair by surface and internal modification Scientific reports · 2019 · 17 citations
    10. On the effects of a plant extract of Orthosiphon stamineus on sebum-related skin imperfections International Journal of Cosmetic Science · 2010 · 17 citations
    11. HAIR LOSS FROM SEBUM Archives of Dermatology · 1953 · 13 citations
    12. Sebaceous Gland Regeneration in Human Skin Xenografts Journal of Investigative Dermatology · 2010 · 9 citations
    13. Analysis of Lipids in the Medulla of Japanese Hair and Their Function Cosmetics · 2018 · 7 citations
    14. Free internal lipids in hair from pre‐ and post‐menopausal women International Journal of Cosmetic Science · 2005 · 7 citations
    15. Phytochemical Analysis of Eclipta prostrata L. (L.) Leaves International Journal of Current Microbiology and Applied Sciences · 2018 · 4 citations
    16. Refatting rate of human hair lipids after exposure to selenium disulphide detergents International Journal of Cosmetic Science · 1983 · 2 citations
    17. Experimental and theoretical studies on the interaction of finasteride with chitosan-based nanoniosomes Journal of molecular structure · 2024 · 1 citations
    18. Dual Case Reports for Lipid Loss from Human Hair Archives of Clinical and Medical Case Reports · 2019 · 1 citations
    19. 284 Backhousia citriodora leaf extract: A new active solution to control hyper-seborrhea for multi-ethnic skins Journal of Investigative Dermatology · 2017 · 1 citations
    20. Molecular interactions of natural and synthetic steroids in female hamsters’ flank organs Journal of Dermatological Science · 2012 · 1 citations
    21. Phytochemical profiling, antibacterial, antifungal and antioxidant evaluation of Acrotrema arnottianum Wight - An ethnomedicinal plant Current Botany · 2025
    22. Proximate Composition, Mineral analysis and Phytochemical Characterization of an Ethnomedicinal Plant Sphenodesme involucrata var. paniculata (C.B. Clarke) Munir International Journal of Plant and Environment · 2024
    23. PENGARUH MINYAK KELAPA MURNI DAN MINYAK INTI SAWIT TERHADAP PERTUMBUHAN RAMBUT PADA KELINCI Jurnal Farmanesia · 2021
    24. Isolation, Structural Elucidation and Therapeutic Potentials of Root of Cucurbita pepo 2021
    25. 1302 Disturbed sebum and microbiome composition in sensitive scalp Journal of Investigative Dermatology · 2018
    26. A Topical Scalp Serum Containing Adenosine, MgSO4, Vitamin CG, and Pre- and Probiotic Fractions Reduces Discomfort and Associated Symptoms of Sensitive Scalp Dermatologic therapy · 2023
    27. 34546 A topical antioxidant serum containing silymarin reduces sebum peroxidation and improves facial acne Journal of the American Academy of Dermatology · 2022
    28. P382 Scalp fungal microbiome and sebum composition in males with and without androgenetic alopecia Medical Mycology · 2022
    29. Improvement of Hair Damage by Lipophilic Vitamin C (Ascorbyl Tetraisopalmitate) Journal of Society of Cosmetic Chemists of Japan · 2018
    30. Acne and sebaceous gland function Clinics in dermatology · 2004 · 463 citations