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30 / 482 resultsresearch Restoration of Spermatogenesis and Male Fertility Using an Androgen Receptor Transgene
Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.
![Clomiphene citrate rescue of spermatogenesis in men with infertility while remaining on finasteride: A case report](/images/research/66ef55a4-acd3-466a-9805-d2844a07cdca/small/4001.jpg)
research Clomiphene citrate rescue of spermatogenesis in men with infertility while remaining on finasteride: A case report
Clomiphene citrate improves fertility in men taking finasteride for hair loss.
![Impact of dutasteride on spermatogenesis and oxidative status in rats.](/images/research/8b4eea33-8a70-41b4-8185-fdca4da33b41/small/17486.jpg)
research Impact of dutasteride on spermatogenesis and oxidative status in rats.
Dutasteride did not change rat spermatogenesis or oxidative stress but needs more research.
![The effect of finasteride on spermatogenesis of Mesocricetus auratus](/images/research/95d333f0-a49b-4454-a75a-5ad42e810499/small/2797.jpg)
research The effect of finasteride on spermatogenesis of Mesocricetus auratus
Finasteride causes sperm production decrease in Mesocricetus auratus.
![CHRONIC TREATMENT WITH FINASTERIDE DAILY DOES NOT AFFECT SPERMATOGENESIS OR SEMEN PRODUCTION IN YOUNG MEN](/images/research/145d70ed-d1bc-4cbb-96bf-1aff94166f83/small/2320.jpg)
research CHRONIC TREATMENT WITH FINASTERIDE DAILY DOES NOT AFFECT SPERMATOGENESIS OR SEMEN PRODUCTION IN YOUNG MEN
Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.
![Effects of the chronic use of finasteride on testicular weight and spermatogenesis in Wistar rats](/images/research/19866e34-273b-4543-9f02-b85299baeb49/small/2415.jpg)
research Effects of the chronic use of finasteride on testicular weight and spermatogenesis in Wistar rats
Finasteride doesn't change rat testicle weight or sperm production.
![Effect of 1-mg Dose of Finasteride on Spermatogenesis and Pregnancy](/images/research/ad17bae9-d06d-49d6-b7d1-fb2af0f7ea7f/small/2943.jpg)
research Effect of 1-mg Dose of Finasteride on Spermatogenesis and Pregnancy
Finasteride 1-mg doesn't harm sperm or pregnancy chances.
research Finasteride. Does it affect spermatogenesis and pregnancy?
![RE: CHRONIC TREATMENT WITH FINASTERIDE DAILY DOES NOT AFFECT SPERMATOGENESIS OR SEMEN PRODUCTION IN YOUNG MEN](/images/research/419c28da-9aec-42ad-8da8-73e6abdbb165/small/2321.jpg)
research RE: CHRONIC TREATMENT WITH FINASTERIDE DAILY DOES NOT AFFECT SPERMATOGENESIS OR SEMEN PRODUCTION IN YOUNG MEN
Finasteride daily doesn't affect sperm production or semen in young men.
research CHRONIC TREATMENT WITH FINASTERIDE DAILY DOES NOT AFFECT SPERMATOGENESIS OR SEMEN PRODUCTION IN YOUNG MEN
![Exposure of Xenopus laevis tadpoles to finasteride, an inhibitor of 5-α reductase activity, impairs spermatogenesis and alters hypophyseal feedback mechanisms](/images/research/f41c385e-2aab-4abb-8236-5ce29bfacd5d/small/2903.jpg)
research Exposure of Xenopus laevis tadpoles to finasteride, an inhibitor of 5-α reductase activity, impairs spermatogenesis and alters hypophyseal feedback mechanisms
Finasteride exposure harms tadpole reproduction and hormone balance.
research The effects of Finasteride on the expression of Dazl, Tsga10, Sycp3, Prm2 genes during spermatogenesis in testes of NMRI mice
Finasteride, at doses of 5mg or higher, may negatively affect male fertility by reducing the expression of certain genes involved in sperm production.
![Role of 5α-dihydrotestosterone in testicular development of gilthead seabream following finasteride administration](/images/research/4c3e7313-b260-486e-86a4-b4686a940c4d/small/4142.jpg)
research Role of 5α-dihydrotestosterone in testicular development of gilthead seabream following finasteride administration
DHT affects testicular development and regulates spermatogenesis in some fish.
![Impacto de dutasteride en la espematogénesis y el estrés oxidativo en ratas.](/images/research/b781f2c8-7ceb-4dec-8996-070559178856/small/17485.jpg)
research Impacto de dutasteride en la espematogénesis y el estrés oxidativo en ratas.
Dutasteride does not seem to change rat spermatogenesis or oxidative stress.
research Endocrine Functions of the Testes
The testes produce important hormones like testosterone and others that play key roles in male body functions.
![Reproductive System, Male](/images/research/703d0a33-a247-4f4c-bb2d-7a76f61e23f0/small/14313.jpg)
research Reproductive System, Male
The document explains how sperm cells are produced, the role of testosterone in this process, and how toxins can reduce sperm count and fertility.
research Pharmacological basis for clinical use of antiandrogens
Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by blocking male sex hormones.
![Male hormonal contraception: looking back and moving forward](/images/research/0d0969d1-131a-4273-94a4-d20cabc8b1cf/small/20255.jpg)
research Male hormonal contraception: looking back and moving forward
New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.
![COVID-19 and andrology: Recommendations of the French-speaking society of andrology (Société d’Andrologie de langue Française SALF)](/images/research/7bdb29ac-dfd1-446d-8890-8798ad6cae3c/small/17437.jpg)
research COVID-19 and andrology: Recommendations of the French-speaking society of andrology (Société d’Andrologie de langue Française SALF)
Wait 3 months after COVID-19 before trying assisted reproduction and further research is needed on COVID-19's effects on male hormones and fertility.
![The probable destructive mechanisms behind COVID-19 on male reproduction system and fertility](/images/research/e93e6af0-2459-4f8d-b2ac-effddc7e2988/small/20146.jpg)
research The probable destructive mechanisms behind COVID-19 on male reproduction system and fertility
COVID-19 may harm male fertility and damage the reproductive system.
research Reproductive and Nonreproductive Actions of Testosterone
Testosterone is important for male sexual traits, reproduction, muscle and bone health, blood production, and metabolism, and works both directly and after being changed into other hormones.
![Role of Environmental Factors and Gonadotoxin Exposure in Unexplained Male Infertility](/images/research/9b0a3649-73e8-4f9f-86e9-7cabc13cfd1c/small/14240.jpg)
research Role of Environmental Factors and Gonadotoxin Exposure in Unexplained Male Infertility
Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.
![PHARMACOLOGICAL BASIS FOR CLINICAL USE OF ANTIANDROGENS](/images/research/a12eaef4-a63a-484f-a4e3-bed72029bf97/small/28330.jpg)
research PHARMACOLOGICAL BASIS FOR CLINICAL USE OF ANTIANDROGENS
Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by affecting androgen functions and suppressing certain hormones.
![Physiologic functions of PP2A: Lessons from genetically modified mice](/images/research/ac8b0de1-9a02-4440-bd99-daee7b61ba45/small/19383.jpg)
research Physiologic functions of PP2A: Lessons from genetically modified mice
Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.
research Intratesticular Control Of Steroidogenesis
The testes control steroid production through complex interactions involving various cells and signaling molecules.
![SHISA6 Confers Resistance to Differentiation-Promoting Wnt/β-Catenin Signaling in Mouse Spermatogenic Stem Cells](/images/research/d9660030-0adf-49fa-bbe3-fcadeee73089/small/19561.jpg)
research SHISA6 Confers Resistance to Differentiation-Promoting Wnt/β-Catenin Signaling in Mouse Spermatogenic Stem Cells
SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.
![Adverse effects of common medications on male fertility](/images/research/a227ee09-2321-4614-b893-f24cbb176bd0/small/14270.jpg)
research Adverse effects of common medications on male fertility
Some common medications can harm male fertility, but many effects can be reversed.
![Physiology of the Hypothalamic Pituitary Gonadal Axis in the Male](/images/research/17e3d92b-316b-413b-aaaa-6915a9914620/small/20246.jpg)
research Physiology of the Hypothalamic Pituitary Gonadal Axis in the Male
The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.
![Male gonadal function in coeliac disease: 2. Sex hormones.](/images/research/24b1edbc-14c8-442a-8c91-1007c88aa879/small/28326.jpg)
research Male gonadal function in coeliac disease: 2. Sex hormones.
Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.