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    Glossary SOX2

    gene crucial for stem cell pluripotency and tissue development

    SOX2 is a gene that plays a crucial role in maintaining the self-renewal and pluripotency of stem cells, meaning it helps stem cells stay in a state where they can develop into different types of cells. It is also involved in the development of various tissues, including the nervous system and hair follicles, making it significant in both regenerative medicine and understanding conditions like alopecia.

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    Research 30 of 928

    1. SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair Nature Communications · 2019 · 87 citations
    2. The disruption of Sox21-mediated hair shaft cuticle differentiation causes cyclic alopecia in mice Proceedings of the National Academy of Sciences · 2009 · 73 citations
    3. Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ iScience · 2020 · 22 citations
    4. Expression and localization of Sox10 during hair follicle morphogenesis and induced hair cycle International Journal of Medical Sciences · 2021 · 9 citations
    5. SOX2 in the Skin Elsevier eBooks · 2015 · 1 citations
    6. Study on Effect of Constant-release Melatonin on SOX21 Gene China Animal Husbandry & Veterinary Medicine · 2011
    7. Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis Development · 2009 · 338 citations
    8. Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences between Sox2-Positive and -Negative Cells In Vitro and In Vivo Journal of Investigative Dermatology · 2011 · 68 citations
    9. SKPing a Hurdle: Sox2 and Adult Dermal Stem Cells Cell stem cell · 2009 · 11 citations
    10. Sox2 in the dermal papilla regulates hair follicle pigmentation Cell reports · 2022 · 9 citations
    11. Sox13 is a novel early marker for hair follicle development Biochemical and Biophysical Research Communications · 2019 · 6 citations
    12. Scoparone Induces Expression of Pluripotency Transcription Factors SOX2 and NANOG in Dermal Papilla Cells in Vivo · 2021 · 4 citations
    13. Keratin 75 Is a Component of the LINC Complex and Has an Essential Role in Mediating the SOX2 Rapid Healing Response during Wound Repair 2022 · 3 citations
    14. SOX18 Promotes the Proliferation of Dermal Papilla Cells via the Wnt/β-Catenin Signaling Pathway International Journal of Molecular Sciences · 2023 · 1 citations
    15. Immunohistochemical assessment of SOX10 and its relation to the immune cellular infiltrate in alopecia areata follicles Journal of the Egyptian Womenʼs Dermatologic Society · 2024
    16. Exosomal miR-222-3p derived from dermal papilla cells inhibits melanogenesis in melanocytes by targeting SOX10 in rabbits Animal Bioscience · 2024
    17. A Low Dose of Rapamycin Promotes Hair Cell Differentiation by Enriching SOX2+ Progenitors in the Neonatal Mouse Inner Ear Organoids. PubMed · 2024
    18. 1496 Transcription factor SOX2-induced amphiregulin inhibits pressure ulcer formation via suppressing oxidative stress after cutaneous ischemia-reperfusion in mice Journal of Investigative Dermatology · 2023
    19. 602 Sox13 is a novel marker for hair follicle development and differentiation Journal of Investigative Dermatology · 2019
    20. Major depletion of SOX2+ stem cells in the adult pituitary is not restored which does not affect hormonal cell homeostasis and remodelling Scientific Reports · 2017 · 22 citations
    21. Secretory phospholipase A2-IIA overexpressing mice exhibit cyclic alopecia mediated through aberrant hair shaft differentiation and impaired wound healing response Scientific Reports · 2017 · 7 citations
    22. Deletion of the <i>Sox21</i> gene drastically affects hair lipids Experimental Dermatology · 2012 · 2 citations
    23. Molecular Mechanisms Regulating Hair Follicle Development 2002 · 854 citations
    24. Nerve dependence in tissue, organ, and appendage regeneration Trends in Neurosciences · 2012 · 228 citations
    25. Cartilage to bone transformation during fracture healing is coordinated by the invading vasculature and induction of the core pluripotency genes Development · 2017 · 160 citations
    26. MicroRNA-302 Increases Reprogramming Efficiency via Repression of NR2F2 Stem cells · 2012 · 123 citations
    27. Epidermal patterning and induction of different hair types during mouse embryonic development Birth defects research · 2009 · 81 citations
    28. Dynamic Plasticity of Axons within a Cutaneous Milieu Journal of Neuroscience · 2010 · 79 citations
    29. Direct conversion of mouse and human fibroblasts to functional melanocytes by defined factors Nature Communications · 2014 · 66 citations
    30. Induced Pluripotent Stem Cells from Human Hair Follicle Mesenchymal Stem Cells Stem Cell Reviews and Reports · 2012 · 64 citations