Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, researchers developed microcapsules and effervescent tablets containing policosanol from insect wax, achieving high encapsulation efficiency and rapid water dispersion, effectively addressing the challenges of solubility and psychological acceptance in consuming insect-based lipids.

This study demonstrated that combining amorphization and nanonization of drugs enhances both saturation solubility and dissolution rate, potentially offering therapeutic benefits for formulations like dermal applications.

This study introduced a technology for creating water-soluble minerals, which reportedly showed potential health benefits such as diet and anti-wrinkle effects in their applications.

This study investigated the morphology and growth mechanisms of spherical crystal aggregates of minoxidil in various alcoholic solvents, finding that a n-butanol–ethyl acetate mixture produces unique spherulite aggregates with improved powder characteristics.

This study found that minoxidil had the highest solubility in shea butter, stearic acid, and rosemary oil, suggesting these natural oils may improve drug loading and encapsulation efficiency in lipid nanocarrier formulations for potential hair growth applications.

This review discusses therapeutic deep eutectic solvents as promising "green" solutions for enhancing drug solubility and delivery through the skin, reporting no new clinical results and highlighting future research directions.

This study evaluated a microemulsion-based flushing fluid made with castor oil that effectively removed 84.85% of mud cake formed by drilling fluid, highlighting its Newtonian fluid behavior and high wettability inversion capability.

This study suggests that finasteride-loaded polyvinyl alcohol/chitosan microspheres could be a promising embolic agent for benign prostatic hyperplasia, showing effective occlusion and sustained drug release in preclinical models.

This study explored the development of a self nanoemulsifying drug delivery system to enhance the solubility and oral bioavailability of exemestane HCl for breast cancer therapy.

This study found that Soluplus and L-ascorbyl 2,6-dipalmitate nanoparticles may improve minoxidil's skin permeability through stable hydrophobic interactions, enhancing its potential for targeted skin application.

This study found that POD-loaded solid lipid nanoparticles using 0.5% poloxamer 188 and 1.5% soybean lecithin (P-SLN) improved epidermal targeting and POD accumulation in porcine skin compared to traditional tincture.

This study suggests that using glycosidases to lyse the polysaccharides of Botryoccocus braunii may allow for the semi-continuous recovery of hydrocarbons while keeping the cells viable.

This review summarizes the enhanced absorption and bioavailability of phytosome delivery systems, which combine herbal extracts with phospholipids to improve therapeutic potential, and provides an updated overview of their development, commercial availability, and patented technologies.

This study found that the nonionic surfactant Brij 78 stabilized cationic minoxidil microparticles against aggregation, maintaining their substantivity in the presence of excess anionic surfactant.

This article reviews various strategies, primarily developed by the Turin University Pharmaceutical Technology group, for increasing entrapment efficiency of hydrophilic molecules in nanoparticulate systems and reports no clinical results.

In this study, researchers developed a delivery system using a deep eutectic solvent to improve hydroxytyrosol absorption for hair regrowth, achieving over threefold greater skin penetration compared to aqueous solutions and demonstrating its effectiveness and biocompatibility in hair regrowth and ROS-scavenging tests.

This review highlights how cyclodextrin-polysaccharide hybrids can advance drug delivery and environmental cleanup by improving the solubility and stability of hydrophobic molecules, serving as promising platforms for biomedical applications and efficient sorbents for wastewater treatment.

This study developed a Neusilin® US2-based solid self-nanoemulsifying drug delivery system for finasteride that showed improved stability and drug delivery, with complete dissolution comparable to standard Propecia® tablets.

This study found that using spanlastics, a nano, surfactant-based drug delivery system, improved the bioavailability, drug release characteristics, and pharmacokinetic behavior of famotidine, a poorly soluble drug, by enhancing its dissolution and membrane permeation.

This study found that drying finasteride solvates at 85 °C for one day produced a metastable anhydrous form.

This study optimized conditions for extracting saponins from Eclipta prostrata, achieving maximum yield with specific ethanol concentration, time, temperature, and liquid/solid ratio.

This study found that a combination of 5% DMSO and BSA minimizes toxic effects on the cytogenetic stability of dermal papilla cells during cryopreservation.

This study found that ultrasonically depolymerized ι-carrageenan from Solieria chordalis yields low-molecular-weight fractions that maintain fibroblast viability and show no cytotoxicity, suggesting potential for safe use in human medicine.

This study investigated the physicochemical properties of polystyrene-b-poly(acrylic acid) nanovesicles coated with modified chitosans, finding that they can effectively control surface charge and potentially serve as drug delivery carriers with a 50.7% encapsulation efficiency for minoxidil.

This study found that hair treated with shampoo containing water-soluble silicone demonstrated smoother sliding and better detangling, compared to shampoo with water-insoluble silicone, due to differences in conditioning film formation.

In this study, a new delipidisation method that removes over 97% of key lipids from wool rapidly and without yellowing was reported to improve wool processing and printing quality.

In this study, Eclipta alba phytosomes were developed to enhance the bioavailability and therapeutic efficacy of its bioactive compounds, showing improved in vitro antioxidant activity and significant in vivo anticancer effects compared to the free extract.

In this study, ultradeformable liposomes containing Tween 20 or terpenes increased phospholipid bilayer fluidity and enhanced skin penetration of sodium fluorescein, with terpenes improving hair follicle penetration.

This study found that a nano-cubosome formulation co-loaded with capsaicin and thiocolchicoside enhanced bioavailability and showed promising analgesic and anti-inflammatory effects in rats, potentially benefiting gout management through improved transdermal delivery.