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270-300 / 1000+ resultsresearch Incorporation of benzoyl peroxide nanocrystals into adapalene-loaded solid lipid microparticles: Part II – Solid-in-Oil dispersion of nanoparticulate benzoyl peroxide
This work explores using a liquid crystalline phase to stabilize benzoyl peroxide nanosuspensions, suggesting a promising method to potentially reduce the side effects of acne treatments.
research Mechanism of transdermal permeation promotion of lipophilic drugs by ethosomes
In this study, ethosomes were found to improve the skin penetration of a model lipophilic drug more effectively than liposomes or hydroethanolic solutions, suggesting a unique mechanism involving the breakdown of vesicles in the skin.
research Kinetics and Equilibrium of Solute Diffusion into Human Hair
This study found that the uptake of molecules by hair is influenced by both hydrophobic and ionic charge interactions, with binding affinity decreasing as pH approaches the solute's dissociation constant.
research “Formulation and Evaluation of Minoxidil Fast Dissolving Tablet”
This study designed fast-dissolving Minoxidil tablets to improve patient compliance and found that formulations containing 6% croscarmellose sodium were optimal, showing rapid in-vitro dispersion and effective drug release without drug interaction.
research Self-Emulsifying Drug Delivery Systems (SEDDS): Measuring Energy Dynamics to Determine Thermodynamic and Kinetic Stability
This study observed that a self-emulsifying drug delivery system for finasteride significantly enhanced bioavailability in rats compared to commercial tablets, but the formulation was found to be thermodynamically unstable.
research Determination of Free Chemical Potential for Finasteride Diffusion through SDS Micelle Suggested as Alternative Living Membrane System
This study found that Finasteride may spontaneously diffuse into an SDS-based model cell membrane at a significant rate, with distinct behavior in polar and non-polar solutions.
research Study preparation of Finasteride Dispersible Tablets and its vitro dissolution
This study found that Finasteride Dispersible Tablets, prepared with an optimized prescription, disintegrate quickly, disperse well, and have a high dissolution speed, suitable for industrial production.
research Mechanistic study of decreased skin penetration using a combination of sonophoresis with sodium fluorescein-loaded PEGylated liposomes with D-limonene
This study found that low-frequency sonophoresis significantly decreased the skin penetration of sodium fluorescein-loaded PEGylated liposomes with D-limonene and affected percutaneous absorption by partially plugging hair follicle orifices.
research Production of a Biosurfactant for Application in the Cosmetics Industry
In this study, researchers produced a biosurfactant from yeast that effectively reduces surface tension, acts as a good oil emulsifier, demonstrates antioxidant and antimicrobial properties, and exhibits no cytotoxicity, suggesting its potential use in eco-friendly cosmetic formulations.
research Experimental and thermodynamic analyses of supercritical CO2-Solubility of minoxidil as an antihypertensive drug
In this study, researchers measured the solubility of Minoxidil in supercritical CO₂ under various temperature and pressure conditions and created models to estimate solubility based on different predictive approaches.
research Emulgel: A Novel Approach For Hydrophobic Drugs
In this study, researchers highlighted that emulgels, a combination of emulsions and gels, offer a novel topical delivery method for hydrophobic drugs, possessing attributes such as easy spreadability and bio-friendliness, making them suitable for conditions like acne, fungal infections, and psoriasis.
research 0870 Improving the stability of retinol: Overcoming obstacles through solid lipid particle technology
Solid Lipid Particle technology makes retinol more stable, effective, and gentle on the skin.
research Optimization of menthol-loaded nanocapsules for skin application using the response surface methodology
This study developed lipid-core nanocapsules for encapsulating menthol, improving its solubility and thermal stability, and demonstrated their safety and rapid skin absorption in ex vivo tests, highlighting potential applications for cosmeceuticals.
research Efficient Intradermal Delivery of Superoxide Dismutase Using a Combination of Liposomes and Iontophoresis for Protection against UV-Induced Skin Damage
This study found that using a combination of iontophoresis and liposomal delivery facilitated the effective intradermal administration of superoxide dismutase in rats, reducing oxidative skin damage from UV exposure.
research A Comprehensive Review on Deep Eutectic Solvents and Its Use to Extract Bioactive Compounds of Pharmaceutical Interest
This paper reviews the properties, characteristics, and applications of deep eutectic solvents as environmentally friendly alternatives for extracting bioactive compounds from natural sources in the pharmaceutical industry.
research Preparation, characterization and evaluation of finasteride ethosomes
This study found that finasteride ethosome formulations with specific ethanol and soya lecithin concentrations significantly enhanced transdermal drug delivery compared to a potential nanogel.
research Differentiation of nitrogen-fixing nodules of Sesbania rostrata with special reference to oleosomes (lipid bodies)
This study suggests that oleosomes in Sesbania nodules are utilized for cell growth and development but are not directly involved in nitrogen fixation.
research Studies on lysosomes—XIII
This study found that stilbamidine and hydroxystilbamidine can inhibit the release of specific enzymes from lysosomes and mitochondria in rabbit liver at certain concentrations, with effects similar to cortisol and chloroquine.
research Assessment on the Effects of Liposome-encapsulated Thioglycolic Acid on Hair Perming
In this study, liposome-encapsulated thioglycolic acid improved hair perming by enhancing the penetration of perm solutions, resulting in a stronger S-shaped wave and higher cysteine content compared to the control.
research A Comprehensive Review on Deep Eutectic Solvents and Its Use to Extract Bioactive Compounds of Pharmaceutical Interest
This review describes deep eutectic solvents as a green alternative to toxic solvents in extracting bioactive compounds, highlighting their sustainability, production from natural ingredients, and beneficial properties for pharmaceutical applications.
research Development and Characterization of In Situ Gelling Nasal Cilostazol Spanlastics
This study developed cilostazol-loaded formulations for nose-to-brain delivery, finding that these formulations improved cilostazol's bioavailability by enhancing solubility, absorption, and permeability, achieving nearly 100% drug release in vitro within 2 hours.
research Preparation and in vitro evaluation of protective effects of Silibinin‐loaded polymeric micelles on human hair against UV‐B radiation
This study found that Silibinin-loaded polymeric micelles significantly protected human hair from UV-B induced structural and chemical damage by preventing increases in roughness and reducing protein loss.
research Polymeric micelle mediated follicular delivery of spironolactone: Targeting the mineralocorticoid receptor to prevent glucocorticoid-induced activation and delayed cutaneous wound healing
This study found that polymeric micelle nanocarriers delivered pharmacologically relevant amounts of spironolactone to the epidermis and upper dermis, with higher delivery to pilosebaceous units, suggesting potential for treating glucocorticoid-induced impaired wound healing and pilosebaceous androgen-related skin diseases.
research Quantitative Bestimmung von kosmetischen Wirk- und Pflegesubstanzen auf dem Haar
This study developed analytical methods to better understand hair treatment with cosmetic formulations, revealing that active agents primarily adsorb on the hair surface during short washes.
research Promising protocol for in vivo experiments with betulin
This study found that a combination of betulin and cytostatic Namitecan had a statistically significant synergistic effect on solid Ehrlich adenocarcinoma tumors in NMRI mice, and suggests a promising method for administering betulin in in vivo experiments despite its water insolubility.
research Temperature-dependent phase transition microemulsions for enhanced transdermal delivery of finasteride and silodosin
This study evaluated a menthol-based microemulsion for transdermal delivery of finasteride and silodosin, finding that it enhanced skin permeation and flux compared to aqueous solutions, suggesting a promising method for managing benign prostatic hyperplasia.
research Screening and identification of efficient strain in selenium oxyanions sorption in order to biological wastewater treatment
This study found that an Enterobacter isolate demonstrated high resistance to selenate and effective sorption capacity, suggesting potential for bioremediation of selenium-contaminated environments.
research Enhanced Skin Permeation and Controlled Release of β-Sitosterol Using Cubosomes Encrusted with Dissolving Microneedles for the Management of Alopecia
This study found that cubosomes combined with dissolving microneedles enhanced transdermal penetration and hair growth efficacy of beta-sitosterol for treating alopecia.
research Modelling of the composition of emulsion medicines and cosmetics stabilized by a biocomplex of surfactant substances based on rhamnolipids Pseudomonas sp. PS-17
This study explored a computer simulation method for selecting emulsion compositions in dermatology, finding that the PS biocomplex can be effectively used as an emulsifier or co-emulsifier, which streamlines the development process and reduces experimental demands.