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The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

Low-level Laser Therapy may help reduce inflammation, pain, and aid healing, but more research is needed to confirm its effectiveness and establish standard treatment guidelines.

Hair growth is cyclic and influenced mainly by local factors.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Fat-related cells are important for initiating hair growth.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Rosacea is a skin condition with unclear causes, classified into four subtypes.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Tofacitinib is effective and safe for severe hair loss, but full regrowth is less likely after 10 years of hair loss.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Different types of skin cells play specific roles in development, healing, and cancer.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.