97 citations
,
May 2008 in “Journal of Cutaneous Pathology” This review highlights the challenges in identifying histological features of adverse reactions to soft tissue fillers and emphasizes the need for increased awareness due to product uncertainty and delayed reactions.
70 citations
,
February 2021 in “International Journal of Molecular Sciences” This review provides an overview of current research on AD-MSCs, PRP, and biomaterials, highlighting their safety and efficacy in treating soft tissue defects and chronic wounds without major side effects.
18 citations
,
November 2008 in “Disease-a-Month” This study developed a multifunctional injectable hydrogel that effectively provided hemostasis and accelerated healing of infected skin wounds, demonstrating significant potential for clinical wound dressing applications.
14 citations
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August 2017 in “Dermatologic surgery” This review discusses strategies for achieving natural results in male facial aging treatments using dermal and subcutaneous fillers, but reports no new clinical outcomes.
12 citations
,
November 2018 in “Aesthetic plastic surgery” In this study, autologous fibroblasts combined with keratin gel were reported to effectively and safely improve tear trough deformities up to 24 months post-injection, with no severe adverse effects observed.
8 citations
,
November 2010 in “Facial Plastic Surgery” This review discusses the limitations and techniques of fat transfer for facial rejuvenation, focusing on achieving safe and long-term aesthetic outcomes without providing new clinical results.
5 citations
,
June 2025 in “Journal of Functional Biomaterials” This study explored recent advancements in 3D bioprinting for head and neck defects, highlighting how bioinks and scaffolds may improve treatment customization and functionality by mimicking native tissue features. The research also examined challenges like biocompatibility and regulatory requirements on the path to clinical use.
1 citations
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August 2019 in “Journal of Dentistry Indonesia” This ex vivo study reported that a 645-nm wavelength red-light laser can penetrate and reach cells in the various layers of swine oral mucosa and periosteum tissue samples.
January 2025 in “Journal of Inorganic Materials” Bioactive inorganic materials show promise in repairing and regenerating soft tissues like skin and nerves.
This chapter reviews secondary soft tissue revision surgeries for residual defects in patients with orofacial clefts, highlighting the various aesthetic issues and their surgical management after reaching skeletal maturity.
This case report describes a 68-year-old patient with mild Sars-Cov2 infection who developed rapidly progressing bullous and necrotic skin lesions leading to osteomyelitis.
April 2020 in “Rice Research Repository (Rice University)” This study suggests that MultiDomain Peptide hydrogels may support wound healing in diabetic mice by accelerating closure and promoting tissue regeneration, though they did not inhibit bacterial growth in infected wounds as expected.
April 2018 in “International journal of nanotechnology and nanomedicine” In this double-blind, placebo-controlled study, researchers found that low-level laser therapy significantly improved the healing rate and reduced the area of pressure ulcers in patients compared to placebo, suggesting its effectiveness in managing ulcers resistant to conventional treatments.
November 2014 in “Springer eBooks” Using a patient's own tissue for browlifting can improve both the position and fullness of the brow for a longer-lasting rejuvenation.
January 2008 in “Chinese Journal of Aesthetic and Plastic Surgery” In this study, the authors found that rabbit hair material ground for 8 hours had better suitability and histocompatibility for injectable soft tissue augmentation compared to other tested formulations.
This study found that an injectable hair material showed good biocompatibility in micropigs and effectively promoted dermal thickening, suggesting its potential as a new soft tissue filler.
January 2008 in “Chinese Journal of Aesthetic and Plastic Surgery” This study found that an injectable material derived from hair shows good biocompatibility and promotes dermal thickness in pigs, suggesting potential as a new soft tissue filling agent.
January 1982 in “Japanese Journal of Clinical Immunology” This case study reports the rare occurrence of widespread soft-tissue calcification in a young patient with SLE, suggesting that 99mTe-phosphate compounds could help diagnose this complication.
9 citations
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May 2012 in “Journal of Craniofacial Surgery” This study reports that reconstructing perioral soft tissue defects with submental tissue resulted in satisfactory aesthetic outcomes and minimal donor-site morbidity.
17 citations
,
May 2023 in “Aesthetic Plastic Surgery” This review found that among emerging technologies for skin anti-aging, stem cell therapies using recipient chimerism might be more beneficial than CRISPR-Cas9 and other current innovations, though further studies on safety and efficacy are needed.
2 citations
,
April 2023 in “Stem Cell Research & Therapy” This study found that small extracellular vesicles derived from human adipose tissue could promote soft tissue regeneration and increase M2 macrophage polarization, suggesting a promising cell-free approach to tissue repair.
February 2025 in “Seminars in Plastic Surgery” This review addresses the complex process of reconstructing gunshot-induced facial injuries, highlighting advancements in composite tissue transplants and allografts that enhance plastic surgeons' ability to achieve optimal aesthetic and functional outcomes despite significant challenges.
June 2003 in “Clinical orthopaedics and related research” This case study reports a rare instance of Majocchi's granuloma caused by Candida, highlighting the patient's diabetes mellitus and kidney transplant as predisposing factors for the infection.
18 citations
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September 2020 in “International Journal of Nanomedicine” This study found that both allogeneic and xenogeneic small extracellular vesicles from adipose tissue similarly enhanced soft tissue regeneration and wound healing in rat models, implying similar therapeutic effects across species.
January 2024 in “Defence life science journal” This review explores the potential of non-invasive photobiomodulation therapy for managing combat and traumatic soft tissue injuries, emphasizing its benefits, efficacy, and underlying mechanisms, but reports no new clinical results.
101 citations
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July 2021 in “Nature Communications” This study reported that 4D-printed, aliphatic polycarbonate-based scaffolds supported adipose tissue engineering by allowing adipocyte infiltration and neovascularization in vivo, indicating potential for effective adipose tissue repair.
October 2025 in “The Laryngoscope” In this study, hairline lowering using the Endotine Forehead-mini showed significant, sustained improvement in facial harmony with a reduction in the upper facial third ratio; however, 26% of patients experienced complications, including transient alopecia and the need for additional surgery.
11 citations
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January 1957 in “Journal of Histochemistry & Cytochemistry” This study demonstrated radiocalcium uptake in skin, eye, cartilage, and mucous glands, with the highest concentration in the hair follicle's keratogenous zone.
6 citations
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January 1997 in “Pediatric dermatology” This case report highlights a 21-year-old man with severe nodulocystic acne resistant to conventional treatments, who showed moderate improvement with isotretinoin, and discusses its potential link to congenital digital abnormalities and Apert syndrome.
4 citations
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January 1987 in “Beiträge zur Onkologie/Contributions to oncology” This study reported a 21% partial remission rate in patients with advanced soft tissue sarcomas treated with ifosfamide combination chemotherapy, with no complete remissions observed.