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NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.

Some drugs have gained approval for new uses, while others like tricyclic antidepressants and aspirin show promise but aren't yet approved for these uses.

Removing the outer skin layer increases drug absorption and offers non-invasive treatment options, with some methods allowing for quick skin recovery.

The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.

The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.

Some existing drugs and natural products might work against COVID-19 by targeting the virus's main protease.

Diet and supplements can significantly affect acne, with some foods and nutrients reducing and others worsening it.

The document concludes that Borrelia afzelii causes a skin condition in France, a gene is linked to hair loss in Caucasian women, and various genetic mutations affect skin diseases.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

Rosacea is a skin condition with unclear causes, classified into four subtypes.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

New effective scar treatments are urgently needed due to the current options' limited success.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Peptide hydrogels heal burn wounds faster and better than standard dressings.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.