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Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

Androgen receptors found in monkey scalps, similar to humans, affect hair growth.

Skin RAGE levels are linked to inflammation and cell death.

Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.

Human skin responds to light with protective mechanisms, but more research is needed to understand these processes and their implications for health and therapy.

Removing a testicular tumor in a dog reduced its aggressive behavior and skin problems.

New drugs targeting the JAK-STAT pathway show promise for treating inflammatory skin diseases.

Skin bacteria can help wound healing by activating certain immune cells.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.

Females have higher estrogen receptor levels in hair than males, and these levels decrease in white hair compared to black hair.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Fat-related cells are important for initiating hair growth.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.