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This review discusses the evolution and development of smart and multifunctional microneedles, highlighting their potential future importance in medical applications, but it reports no new experimental results.

This study explains surgical techniques for hair transplantation using the sharp implanter method, emphasizing 11 key principles that optimize efficiency and precision, and reports high graft survival and natural hair density when these principles are followed.

This chapter reviews the combined use of platelet-rich plasma and microneedling for cosmetic enhancement but reports no clinical results; the authors highlight existing uses and suggest potential synergistic benefits in dermatology.

This review summarizes recent research on microneedles for alopecia treatment and hair regrowth, noting their potential to improve drug delivery and patient outcomes, but reports no new clinical results.

This review article discusses microneedling as a non-surgical treatment option in dermatology, highlighting its benefits for scar improvement through collagen induction and reporting its popularity among practitioners due to its cost-effectiveness and simplicity.

In this study, researchers developed a novel zinc oxide nanoflower-infused nanocomposite that demonstrated promising results in accelerating wound healing in a murine model, with enhanced angiogenesis, reduced inflammation, and improved collagen deposition compared to a control group.

This review highlights how advanced nanocarrier and microneedle-based transdermal drug delivery strategies can potentially improve the treatment of skin diseases by enhancing site-specific drug delivery, increasing skin penetration, and reducing systemic toxicity compared to conventional methods.

In this study, researchers developed a novel 3D bio-printed skin scaffold using exosomes from liver cells, which enhanced wound healing by promoting cell growth, angiogenesis, and reducing inflammation in large skin injuries, suggesting potential applications in treating chronic skin conditions.

This article explains that skin microneedling promotes skin regeneration by creating microinjuries, which stimulate collagen and elastin production, making it effective for treating various skin issues with high effectiveness, limited side effects, and a short recovery time.

This source reviews advancements in microneedle-based cosmeceutical delivery, discussing new technologies and highlighting a burgeoning area of research involving microneedling combined with stem cell delivery for anti-aging, without finding measurable changes in skin barrier function or appearance during the study period.

This review explores the development and cosmeceutical applications of microneedles for skin treatment, without reporting new clinical results, emphasizing safety and public perception as key factors for commercialization.

This case study describes the successful treatment of facial pigmentation using microneedling combined with platelet-rich plasma, suggesting high effectiveness with minimal side effects in this application.

This review summarizes the application of microneedles in treating various skin diseases and highlights challenges like low drug loading, noting no new clinical results are reported.

This review highlights microneedling's promise as an adjuvant therapy for enhanced drug delivery in dermatology, especially for conditions like atrophic scars and pigmentation disorders, though its efficacy for vitiligo is limited.

This review discusses the use of derma rollers for cosmetic purposes and their potential in transdermal drug delivery by summarizing evidence on their design, efficacy, safety, and concerns from preclinical and clinical reports.

This review explores the potential of microneedling as a drug delivery system for treating melasma, focusing on its mechanisms, safety, efficacy, and clinical advantages over conventional therapies like hydroquinone and lasers.

This literature review conducted a comprehensive analysis of existing studies on micro-needling mesotherapy in dermatology and aims to offer a practical guide for its clinical application, though it provides no new experimental findings.

This study found that bioactive extracts from goat placenta, particularly when delivered via dissolving microneedles, enhanced fibroblast proliferation and skin regeneration without being toxic to skin cells, suggesting a promising dermal application for improving skin health.

This review outlines the development, applications, and challenges of microneedle-based drug delivery from 2000-2019, particularly highlighting fabrication techniques, but reports no new clinical results.

This article reviews the diagnosis and management of inherited epidermolysis bullosa and reports no new clinical findings; it emphasizes the importance of clinical and histopathological evaluation.

This study reviewed eight studies investigating transcutaneous drug delivery via fractional laser and microneedling for alopecia treatment, with six studies showing improved hair regrowth over topical therapy alone, suggesting its potential as a promising treatment strategy, although further research is needed to refine treatment parameters.

This case study reports the first clinical case of besnoitiosis in two donkeys in Italy, suggesting a wider distribution of the disease in European equids than previously expected.

This review suggests that platelet-rich plasma shows potential for improving alopecia areata and skin rejuvenation, but more research is needed as evidence primarily supports short-term outcomes in orthopaedic applications.

This article reviews clinical issues and dermatologist perspectives on managing periungual lesions in patients undergoing docetaxel chemotherapy, but it reports no new clinical outcomes.

This study observed that microneedling induced significant hair regrowth and reduced hyperpigmentation in two Pomeranians with alopecia X, with stable results over 12 months.

Dermoscopy is useful for many health professionals, not just dermatologists, in improving skin condition diagnoses and reducing unnecessary biopsies.

This review discusses the cosmetic applications and healing phases of microneedling and reports no new clinical findings; the authors highlight its use for skin and hair treatments without epidermal damage.

This research found that STAR particles, ceramic particles with microneedles, significantly enhance skin permeability and improve the topical delivery of drugs like minoxidil and acyclovir, effectively promoting or inhibiting hair growth without causing skin irritation in ex vivo pig skin and rat models.

This review discusses various microneedle technologies for long-acting drug delivery, highlighting design considerations and challenges in bringing these minimally invasive devices to market, but it reports no new clinical results.

This review discusses completed and ongoing clinical studies on microneedle-based technologies for cosmetic, therapeutic, and diagnostic applications and reports no new clinical results.