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    Glossary Skin Necrosis

    cells die due to lack of blood supply or severe injury

    Skin necrosis, also known as tissue death, occurs when skin cells die due to a lack of blood supply, infection, or severe injury. This condition can lead to blackened, dead tissue that may require medical intervention to remove and treat the underlying cause.

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    1. Efficacy of Percutaneous Superficial Temporal Arterial Hyaluronidase Injection for Hyaluronic Acid Filler–Induced Necrosis of Frontotemporal Skin and/or the Ipsilateral Scalp With Subsequent Alopecia Aesthetic surgery journal · 2022 · 4 citations
    2. A Rapidly Progressive Case of Skin and Soft Tissues Necrosis in a COVID-19 Positive Patient 2022
    3. Data from Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice 2023
    4. Data from Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice 2023
    5. Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice Cancer Research · 2009 · 53 citations
    6. Tumour Necrosis Factor Alpha, Interferon Gamma and Substance P Are Novel Modulators of Extrapituitary Prolactin Expression in Human Skin PLOS ONE · 2013 · 24 citations
    7. Disease modifying agent related skin reactions in multiple sclerosis: prevention, assessment, and management Multiple Sclerosis Journal · 2004 · 37 citations
    8. Bariatric Surgery and Its Effects on the Skin and Skin Diseases Obesity Surgery · 2013 · 30 citations
    9. Reversible Alopecia with Localized Scalp Necrosis After Accidental Embolization of the Parietal Artery with Hyaluronic Acid Aesthetic plastic surgery · 2017 · 26 citations
    10. Cutaneous necrosis after injection of polyethylene glycol–modified interferon alfa Journal of The American Academy of Dermatology · 2005 · 26 citations
    11. Localized cutaneous necrosis associated with the antiphospholipid syndrome Australasian Journal of Dermatology · 2002 · 16 citations
    12. Testosterone Prevents Cutaneous Ischemia and Necrosis in Males Through Complementary Estrogenic and Androgenic Actions Arteriosclerosis, thrombosis, and vascular biology · 2017 · 12 citations
    13. Generalised cutaneous necrosis: a complication of low-molecular-weight heparin International Wound Journal · 2005 · 11 citations
    14. Sodium Valproate Improves Skin Flap Survival via Gamma-Aminobutyric Acid and Histone Deacetylase Inhibitory System 2019 · 8 citations
    15. Successful management of a large feline skin defect using xenogeneic bovine amniotic membrane: a case report BMC Veterinary Research · 2026
    16. Treacherous territory: Temple fillers and tissue necrosis Skin health and disease · 2024
    17. Activating autophagy promotes skin regeneration induced by mechanical stretch during tissue expansion Burns and trauma · 2024
    18. Complications and Difficult Cases: A Case Report of Central Area Necrosis Following a Hair Transplant Procedure Hair transplant forum international · 2014
    19. The early changes in mouse skin following topical application of a range of middle distillate oil products Journal of Applied Toxicology · 1993 · 19 citations
    20. Epidermal Notch1 recruits RORγ+ group 3 innate lymphoid cells to orchestrate normal skin repair Nature Communications · 2016 · 86 citations
    21. Animal Study of Skin Resurfacing Using the Ultrapulse Carbon Dioxide Laser Annals of Plastic Surgery · 1995 · 69 citations
    22. Gsdma3 Mutation Causes Bulge Stem Cell Depletion and Alopecia Mediated by Skin Inflammation American Journal Of Pathology · 2011 · 54 citations
    23. Neuroimmunoregulation of Androgens in the Adrenal Gland and the Skin Hormone Research in Paediatrics · 2000 · 48 citations
    24. An Animal Model of Trichloroethylene-Induced Skin Sensitization in BALB/c Mice International journal of toxicology · 2015 · 36 citations
    25. Inducible expression of gasdermin A3 in the epidermis causes epidermal hyperplasia and skin inflammation Experimental Dermatology · 2015 · 12 citations
    26. Single dose gamma irradiation induced angiogenesis in rat skin hair follicles Internatuinal Journal of Radiation Research · 2020 · 3 citations
    27. Network pharmacology and in vivo experimental analysis for validating the antifibrotic potential of Punica granatum leaves against skin scleroderma: the role of oxidative stress, inflammation and TGF-β1/Snail 1/p-Smad 3 signaling pathway Inflammopharmacology · 2026
    28. Periplaneta americana extract (L.) promotes hair regrowth in Alopecia areata mice by reducing inflammation and modulating skin microbiota Frontiers in Pharmacology · 2025
    29. 1326 Translation-dependent skin hyperplasia is promoted by type 1/17 inflammation in psoriasis Journal of Investigative Dermatology · 2023
    30. Topical olive oil with downregulation of stress factors protects mice skin from precarious 3600 MHz electromagnetic radiation. The Egyptian Journal of Histology · 2020