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Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Syndecan-1 is essential for maintaining skin fat and preventing cold stress.

Skin problems are very common in people with end-stage kidney disease.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

Reconstructed skin models are useful for studying how skin processes certain chemicals.

Changes in the SREBF1 gene cause a rare genetic skin and hair disorder.

Phospholipase A2 enzymes play key roles in skin health and disease.

Vitamin D receptor is crucial for skin wound healing.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.

Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.

New treatments for skin diseases are more effective and patient-friendly, but many still lack a cure.

Skin cells from people with Epidermolysis Bullosa Simplex have abnormally placed and less active mitochondria.

PPAR-γ may be a key target for treating alopecia areata and other skin conditions.

Scarred skin in lichen planopilaris loses immune cells due to a decrease in a specific protein in skin cells.

HIF-1A may aid hair growth, Backhousia citriodora improves skin, autologous cells stabilize hair loss, infrared thermography assesses alopecia, and a new treatment preserves hair.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

Biotin is important for metabolism, with specific daily intake recommendations, and deficiency can cause health problems.

Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.

SCD1 is important for hair growth by keeping the connection in skin cells where hair stem cells live stable.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Sdr16c5 and Sdr16c6 genes regulate a key point in lipid production that affects eye and skin gland function.

The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.

PCOS in lean women is a serious health condition with implications beyond fertility, affecting metabolism and increasing cardiovascular disease risk.

Valproic acid treatment increases a specific acid in urine by blocking an enzyme, possibly causing skin rash and hair loss.

Leptin, a hormone from fat cells, affects immune responses and can influence skin diseases and hair growth.

Testosterone is important for male sexual traits, reproduction, muscle and bone health, blood production, and metabolism, and works both directly and after being changed into other hormones.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.