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The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Macrophages are essential for successful skin growth in reconstructive surgery.

Vesicular carriers like liposomes may improve cosmetic skin treatment delivery and effectiveness but need more human research.

MRI can effectively image skin structures noninvasively.

Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.

New technologies help us better understand how skin microbes affect skin diseases.

Method measures latanoprost and minoxidil in skin accurately and precisely.

Testosterone can cause acne and male-pattern baldness, affects hair growth in men and women, and makes male skin more sensitive.

Gentamicin penetrates pig skin better through open hair follicles than blocked ones.

DDAIP-HCl significantly increases minoxidil absorption into the skin.

Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.

Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.

The simulation showed that hypobaric pressure improves drug delivery through the skin, but stretching alone doesn't fully explain the increase.

Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.

Skin's uneven surface and hair follicles affect its stress and strain but don't change its overall strength, and help prevent the skin from peeling apart.

Higher power CO2 laser causes more severe skin burns and damage.

Niosomes improve minoxidil skin delivery for hair loss treatment.

Sulforaphane from broccoli can help protect skin from sun damage.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Nanoemulsion creams with certain enhancers can greatly increase caffeine delivery through skin.

Using a special laser can improve how well hair loss treatments get into the skin and hair follicles.

Researchers created better skin-application menthol capsules that are stable, safe, and penetrate the skin quickly.

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.