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    Glossary Skin Integrity

    health and intactness of skin as a protective barrier

    Skin integrity refers to the health and intactness of the skin, which acts as a barrier protecting the body from infections, injuries, and dehydration. Maintaining good skin integrity involves ensuring the skin is free from wounds, ulcers, or other damage, and is crucial for overall health, especially in individuals with conditions like diabetes or those who are bedridden.

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    1. 259 Scalp hair follicle dermal sheath fibroblasts express genes associated with promotion of skin integrity/wound healing and prevention of autoimmune responses in Recessive Dystrophic Epidermolysis Bullosa Journal of Investigative Dermatology · 2024
    2. An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin Developmental cell · 2015 · 173 citations
    3. Efficient integration of human skin single-cell RNA sequencing data 2025
    4. Efficient integration of human skin single-cell RNA sequencing data 2025
    5. Synergistic Innovative Therapies in Dermatology: Integrating Platelet Derivatives, Biomaterials, and Exogenous Bioactive Substances for Enhancing Skin Repair and Regeneration Drug Design Development and Therapy · 2025
    6. Integrating stem cell biology and organoid technology for skin regenerative therapies Health engineering. · 2025
    7. Integrated evaluation of umbilical cord mesenchymal stromal cell-derived extracellular vesicles across skin-related cellular and zebrafish models Frontiers in Bioengineering and Biotechnology · 2026
    8. Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease Stem cell biology and regenerative medicine · 2018
    9. Generation and integration of hair follicle-primed spheroids in bioengineered skin constructs Biomedical Materials · 2022 · 8 citations
    10. Skin health and integrity Elsevier eBooks · 2019 · 7 citations
    11. A Multidimensional Study Integrating Traditional Chinese Medicine and Network Pharmacology: Exploring the Skin Repair and Anti-Aging Effects of a Specific Combination of Five-Colored Plants Clinical Cosmetic and Investigational Dermatology · 2025
    12. JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin Nature Communications · 2018 · 48 citations
    13. Loss of ‘Epidermal Melanin Unit’ Integrity in Human Skin During Melanoma-Genesis Frontiers in oncology · 2022 · 13 citations
    14. LB1256 TRIV-509, a dual inhibitor of KLK5 and KLK7, rapidly improves barrier integrity and markers of epidermal differentiation in atopic dermatitis skin explants Journal of Investigative Dermatology · 2025
    15. Multimodal Non-Invasive Skin Imaging in Dermatology: Current Modalities, Clinical Applications, and Future Integration Diagnostics · 2026
    16. Integrated single-cell RNA-sequencing data of unwounded and wounded mouse skin and fibroblasts. Zenodo (CERN European Organization for Nuclear Research) · 2023
    17. Integrated single-cell RNA-sequencing data of unwounded and wounded mouse skin and fibroblasts. Zenodo (CERN European Organization for Nuclear Research) · 2023
    18. Role of Stearoyl-CoA Desaturase-1 in Skin Integrity and Whole Body Energy Balance Journal of Biological Chemistry · 2013 · 67 citations
    19. Bioengineering strategies for regeneration of skin integrity: A literature review Regenerative Therapy · 2024
    20. Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model Barrier Immunity · 2025 · 1 citations
    21. Anti-inflammatory role of 15-lipoxygenase contributes to the maintenance of skin integrity in mice Scientific Reports · 2018 · 29 citations
    22. Reconstructed human skin shows epidermal invagination towards integrated neopapillae indicating early hair follicle formation in vitro Journal of Tissue Engineering and Regenerative Medicine · 2020 · 29 citations
    23. A Multiaxial Bioreactor Integrated with an Environmental Monitoring System for Tissue‐Engineered Skin Grafts Advanced Healthcare Materials · 2026
    24. Nature-skin-based multi-responsive controlled-release electroactive scaffolds for integrated melanoma postoperative relapse prevention and wound therapy Research Square (Research Square) · 2023 · 2 citations
    25. 3D-Printed degradable hair follicle hanging drop scaffolds integrated with tissue engineered skin promotes hair follicle regeneration in vitro International Journal of Bioprinting · 2025
    26. Integrated single-cell chromatin and transcriptomic analyses of human scalp reveal etiological insights into genetic risk for hair and skin disease bioRxiv (Cold Spring Harbor Laboratory) · 2022
    27. Mutations in AEC syndrome skin reveal a role for p63 in basement membrane adhesion, skin barrier integrity and hair follicle biology British Journal of Dermatology · 2012 · 33 citations
    28. Integrated analysis of long non-coding RNA and mRNA expression in different colored skin of koi carp BMC Genomics · 2019 · 61 citations
    29. Three-Dimensional Cultured Human Dermal Papilla Cells in HGC-Coated Environments Enhance Hair Regeneration and Artificial Skin Integration Biomaterials Research · 2024
    30. Meeting Report: 68th Montagna Symposium on the Biology of Skin “Decoding Complex Skin Diseases: Integrating Genetics, Genomics, and Disease Biology” Journal of Investigative Dermatology · 2020