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    Glossary Skin Integrity

    health and intactness of skin as a protective barrier

    Skin integrity refers to the health and intactness of the skin, which acts as a barrier protecting the body from infections, injuries, and dehydration. Maintaining good skin integrity involves ensuring the skin is free from wounds, ulcers, or other damage, and is crucial for overall health, especially in individuals with conditions like diabetes or those who are bedridden.

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    Research 30 of 1000+

    1. 259 Scalp hair follicle dermal sheath fibroblasts express genes associated with promotion of skin integrity/wound healing and prevention of autoimmune responses in Recessive Dystrophic Epidermolysis Bullosa Journal of Investigative Dermatology · 2024
    2. Integrin signalling regulates YAP/TAZ to control skin homeostasis Development · 2016 · 266 citations
    3. miR-3606-3p alleviates skin fibrosis by integratively suppressing the integrin/FAK, p-AKT/p-ERK, and TGF-β signaling cascades Journal of Advanced Research · 2024 · 15 citations
    4. Integrin α3β1 in hair bulge stem cells modulates CCN2 expression and promotes skin tumorigenesis Life science alliance · 2020 · 5 citations
    5. JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin Nature Communications · 2018 · 48 citations
    6. Skin health and integrity Elsevier eBooks · 2019 · 7 citations
    7. Loss of ‘Epidermal Melanin Unit’ Integrity in Human Skin During Melanoma-Genesis Frontiers in oncology · 2022 · 13 citations
    8. LB1256 TRIV-509, a dual inhibitor of KLK5 and KLK7, rapidly improves barrier integrity and markers of epidermal differentiation in atopic dermatitis skin explants Journal of Investigative Dermatology · 2025
    9. Role of Stearoyl-CoA Desaturase-1 in Skin Integrity and Whole Body Energy Balance Journal of Biological Chemistry · 2013 · 67 citations
    10. Bioengineering strategies for regeneration of skin integrity: A literature review Regenerative Therapy · 2024
    11. Anti-inflammatory role of 15-lipoxygenase contributes to the maintenance of skin integrity in mice Scientific Reports · 2018 · 29 citations
    12. Essential Role for Integrin-Linked Kinase in Melanoblast Colonization of the Skin Journal of Investigative Dermatology · 2019 · 14 citations
    13. Knockout of integrin β1 in induced pluripotent stem cells accelerates skin-wound healing by promoting cell migration in extracellular matrix Stem Cell Research & Therapy · 2022 · 3 citations
    14. Developmentally regulated expression of integrin alpha-6 distinguishes neural crest derivatives in the skin Frontiers in Cell and Developmental Biology · 2023 · 5 citations
    15. Mutations in AEC syndrome skin reveal a role for p63 in basement membrane adhesion, skin barrier integrity and hair follicle biology British Journal of Dermatology · 2012 · 33 citations
    16. Targeted inactivation of integrin-linked kinase in hair follicle stem cells reveals an important modulatory role in skin repair after injury Molecular Biology of the Cell · 2011 · 22 citations
    17. α3β1-integrin regulates hair follicle but not interfollicular morphogenesis in adult epidermis Journal of Cell Science · 2003 · 45 citations
    18. The regenerative potential of skin and the immune system Clinical Cosmetic and Investigational Dermatology · 2019 · 41 citations
    19. β1 Integrins with Individually Disrupted Cytoplasmic NPxY Motifs Are Embryonic Lethal but Partially Active in the Epidermis Journal of Investigative Dermatology · 2013 · 17 citations
    20. Eavesdropping on the conversation between immune cells and the skin epithelium International Immunology · 2019 · 10 citations
    21. Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications International journal of molecular sciences · 2015 · 232 citations
    22. Characterization and Localization of Side Population Cells in Mouse Skin Stem Cells · 2005 · 89 citations
    23. Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Existing in Direct Proximity with the Distal End of the Arrector Pili Muscle Stem Cells International · 2016 · 5 citations
    24. The role of Kindlin-1 in skin homeostasis and tumor development Max Planck Digital Library · 2014
    25. ROLE OF STAT3 IN KERATINOCYTE STEM CELLS DURING SKIN TUMORIGENESIS DigtalCommons @ Texas Medical Center Library (Texas Medical Center) · 2012
    26. Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair Experimental dermatology · 2008 · 160 citations
    27. The role of fibroblast growth factor receptor 2b in skin homeostasis and cancer development The EMBO Journal · 2007 · 125 citations
    28. Keratins and skin disease 2015 · 69 citations
    29. Severe Skin Permeability Barrier Dysfunction in Knockout Mice Deficient in a Fatty Acid ω-Hydroxylase Crucial to Acylceramide Production Journal of Investigative Dermatology · 2019 · 40 citations
    30. Histopathological and Ultrastructural Study of Ectodermal Dysplasia/Skin Fragility Syndrome The American Journal of Dermatopathology · 2005 · 31 citations