4 citations,
October 2011 in “International Journal of Dermatology” Bardet-Biedl syndrome may include under-recognized skin problems related to its metabolic disturbances.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” The STRIPAK complex is crucial for skin cell organization and creating a functional skin barrier.
January 2023 in “Advances in reproductive sciences” Higher levels of the protein Pannexin-1 may play a role in hair loss in women with PCOS.
August 2015 in “Free Radical Biology and Medicine” Some treatments can improve skin's defense against damage, but overuse may cause other skin problems.
1 citations,
October 1984 in “Clinics in dermatology” People distressed by minor skin changes should consult dermatologists with cosmetic expertise, and a public Cosmetic Dermatology Service with mental health support is recommended.
May 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Nicastrin deficiency may cause skin cell damage and pigmentation disorders in humans, similar to effects seen in fish.
April 2016 in “Journal of Investigative Dermatology” Pdgfα signaling helps maintain fat cells in the skin and is important for hair growth, wound healing, and fighting infections.
15 citations,
February 2015 in “Cell & tissue research/Cell and tissue research” P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.
August 2018 in “Journal of Investigative Dermatology” Centrosomes are essential for healthy skin and hair growth, and their role is different from that of cilia.
May 2023 in “ACS Biomaterials Science & Engineering” The scaffold helps wounds heal without scars and promotes hair growth.
50 citations,
September 2014 in “Stem cell reports” BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.
22 citations,
January 2009 in “Advances in experimental medicine and biology” FOXN1 mutations cause severe immunodeficiency, hair loss, nail issues, and thymus defects.
15 citations,
October 2006 in “Journal of the American Academy of Dermatology” Liquid nitrogen spray caused a temporary, harmless swelling under the skin in an elderly woman.
3 citations,
January 2021 in “Veterinary dermatology” A litter of cats had a hair condition similar to a mouse mutation, leading to hair loss and abnormal hair and skin.
67 citations,
September 2003 in “Journal of cutaneous pathology” Skin problems are very common in people with end-stage kidney disease.
61 citations,
April 1969 in “Archives of Dermatology” Skin biopsy is crucial for diagnosing unknown baldness causes.
42 citations,
October 2011 in “Seminars in Cell & Developmental Biology” Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
April 2003 in “Experimental Dermatology” The workshop highlighted the genetic links and psychological impacts of hair loss and skin disorders.
December 2021 in “Folia veterinaria” Over half of the dog skin disorders discussed have known gene variants, enabling genetic testing for diagnosis and responsible breeding.
2 citations,
December 2013 in “Veterinary dermatology” Three dogs with a rare skin condition improved with treatment.
5 citations,
February 2019 in “PloS one” Bald thigh syndrome in sighthounds is caused by structural defects in hair shafts due to downregulated genes and proteins.
August 2014 in “Springer eBooks” Certain gene mutations can weaken the skin barrier and, when combined with environmental factors, lead to eczema and severe itching.
2 citations,
April 2015 in “S. Karger AG eBooks” The document concludes that successful surgical repair of scalp and forehead issues requires careful planning and various techniques depending on the injury or defect size.
January 1989 in “Journal of The American Academy of Dermatology” Psoriasis patients have immune cells that respond more strongly to signals and stimuli due to an intrinsic cellular defect.
Hair keratin treatments can be harmful, potentially causing health issues like skin reactions and cancer.
February 2010 in “Journal of The American Academy of Dermatology” A woman with CHILD syndrome showed skin abnormalities, and the report suggests CHILD nevus and NEVIL might be the same condition, highlighting the need for diagnosis for genetic advice.
34 citations,
October 2004 in “Plastic and Reconstructive Surgery” Nasolabial skin-fat grafts are good for nasal reconstruction with minimal scarring and no need for bolsters, but smoking may affect graft survival.
93 citations,
October 2006 in “The International Journal of Biochemistry & Cell Biology” Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.
73 citations,
December 2010 in “Current opinion in infectious diseases/Current opinion in infectious diseases, with evaluated MEDLINE” Hidradenitis suppurativa is a skin condition possibly caused by hair follicle issues, with treatments focusing on infection and inflammation.
45 citations,
May 2003 in “Journal of Cell Science” α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.