Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study discusses how testosterone exerts its effects directly or through conversion to metabolites, DHT and estradiol 17β, each influencing different physiological processes, noting that DHT conversion is necessary for certain effects but not for muscle, bone, or erythropoiesis impacts.

The project aimed to understand how genetic test results affect patients' actions and feelings in dermatology.

This study suggests that TRPV3 may play a key role in dry skin-related itch, indicating potential for TRPV3 antagonists in treating pruritus resistant to histamine H1R antagonists.

This review explores the role of Eph receptors and ephrins in skin cell processes, discussing their potential for therapeutic targeting in dermatological disorders, but it presents no new research findings.

This study demonstrates that keratinocyte cell lines derived from cultured hair follicles can fully differentiate in organotypic skin models, offering a minimally invasive alternative to obtaining keratinocytes for research.

This review details five cases of syphilitic alopecia, an uncommon symptom in syphilis affecting mainly men, emphasizing that dermatologists should be vigilant as it can appear as the sole symptom.

This study found that diffusion coefficients of chemicals in artificial sebum are significantly higher than those in stratum corneum lipids, suggesting the hair follicle may significantly contribute to transdermal permeation.

This chapter reviews the use of electrospun matrices in creating tissue-engineered skin substitutes and reports no new clinical results; it emphasizes the need for a cell-friendly microenvironment.

This study found that nanoplastics' aggregation behavior on human skin, influenced by factors like concentration, photoaging, and organic constituents, affects their penetration potential through sweat glands and hair follicles, highlighting potential dermal exposure risks.

In this study, Hibiscus rosa-sinensis extract was used to formulate and evaluate herbal cosmetic creams for their antioxidant properties, stability, and effectiveness. The formulations demonstrated strong antioxidant potential, stability under various conditions, and favorable cosmetic qualities, suggesting HRS as a beneficial ingredient in skincare products.

This study found that a combination of photoprotector and nighttime formulations with essential oils improved skin barrier function and structural characteristics in young men's oily, acne-prone, and photoaged skin.

This chapter reviews the presence and roles of stem cells in various body systems, focusing on their lifelong function in animals and humans, and reports no new experimental findings.

This research identified distinct attitudes influencing sunbathing and tanning salon use among female university students, with general attractiveness and skin aging concerns being strong predictors of sun exposure and protection intentions.

This study found that isolated red light may serve as an alternative for photo-immunotherapy without additional photosensitizers, as it did not reduce keratinocyte differentiation markers or increase photo-oxidative damage, unlike treatment with IL-4 or UVA1/blue light.

This article reviews the stages and regulation of the hair cycle, highlighting molecular regulators involved, but it does not present new research findings.

This study found that the circadian clock regulates the activation state of murine epidermal stem cells, affecting tissue homeostasis and susceptibility to tumorigenesis when disrupted.

This review discusses the role of intrinsic skin signals, rather than serum signals, in regulating melanin synthesis and hair pigmentation, but reports no new experimental data.

This review discusses the potential of lecithin organogels for improving topical drug delivery and presents no new experimental results; the authors highlight their stability and low skin irritancy as advantages.

This review discusses the recent advancements in understanding how keratins influence cytoarchitecture, cell dynamics, and disease processes but reports no new clinical results; the authors highlight its roles in development and diseases like cancer.

In this study, researchers found that in hairy guinea pig skin, minoxidil delivered via 40-nm nanoparticles had higher skin penetration than 130-nm nanoparticles, indicating nanoparticle size affects permeation.

This study observed that keratose, derived from human hair, integrated well in mouse tissue and remodeled with collagen, suggesting potential as a non-toxic biomaterial for regenerative applications.

This review discusses recent findings on the plasticity and regulation of epithelial stem cells and reports no new experimental results.

This review examines regenerative hair waves and complex hair cycle domains in transgenic mice, highlighting how these dynamic processes contribute to skin regeneration and the physiological regulation of organs, but reports no new experimental results.

This review discusses the mechanisms and pathways of FGFR signalling and its roles in development, disorders, and therapeutic targeting, but reports no new clinical results.

This review summarizes the major events and regulators of the hair cycle in mammals but reports no new experimental results; it emphasizes the complex regulation of stem cell activation and differentiation during hair growth.

This study found that short-chain fatty acids produced by the skin microbe Propionibacterium acnes may drive inflammatory gene expression in sebocytes, potentially contributing to acne.

This study found that the absence of laminin α5 in adult mice's epidermal basement membrane led to keratinocyte hyperproliferation and immune cell changes, affecting hair follicle development through altered growth factor expression.

This review discusses the use of testosterone therapy for low libido in women, noting mixed evidence on breast cancer risk and a lack of long-term safety data.

In this study, epidermal Notch activation increased jagged 1 expression, leading to skin changes like thickening and blistering, with these effects inhibited when jagged 1 was absent.

The authors concluded that dermal white adipose tissue, influenced by factors like light irradiation, plays a significant role in modulating hair follicle cycles and could be targeted for hair growth treatments.