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This chapter discusses the skin stem cell niche as a complex ecosystem and highlights the diverse components and interactions that influence stem cell function, but it reports no new experimental results.

This article provides an overview of the biological process of skin wound healing, detailing the roles of keratinocytes, dermal cells, and trichogenesis without presenting new experimental results.

In this study using tamoxifen-inducible claudin-1 knockout mice, researchers observed that tight junction barrier leakage induced stratum corneum barrier defects and skin inflammation, suggesting a possible cycle of barrier damage and inflammation in atopic dermatitis.

Retinoic acids temporarily change skin stem cells to a slower cycle and more differentiated state.

This study identified the transcription factor Elf5 as a novel regulator of keratinocyte proliferation and differentiation in skin, with expression elevated in stem/progenitor cell populations, suggesting its potential role in determining cell fate during skin and hair development.

This study found that a combination of botanical extracts from jasmine, Longoza, peony, and lily significantly increased a6 and b4 integrin protein expression in human skin cells, suggesting complementary effects that could enhance skin quality.

This review discusses various stem cell compartments in adult murine and human epidermis, examining their expressed markers and characterization assays, and reports no new experimental results.

In this review, biomaterial-based mechanical strategies were highlighted for their potential to enhance skin regeneration and promote scarless repair, though a comprehensive understanding of their underlying mechanisms is still needed for broader application.

This article reviews the thermoregulation mechanisms in African and Asian elephants and highlights challenges from climate change, with no new empirical results presented.

This case report discusses a doughnut wart recurrence after cryotherapy in a patient with alopecia areata, suggesting autoimmune-related immune imbalance may influence unusual wart behavior.

This case report documents a rare instance of body-focused repetitive behavior in a 37-year-old male physician who compulsively pulled hair from his thighs due to exam stress, highlighting the variability in presentation and demographics of such disorders and the potential for psychiatric comorbidity.

In this laboratory study, researchers developed and tested two in vitro models to simulate atopic dermatitis using HaCaT cells, finding that azithromycin displayed epithelial-strengthening properties in one model, potentially offering insights for future research on skin disease interventions.

This research found that Foxc1 is critical for maintaining quiescence in activated hair follicle stem cells and that the cancer cell-of-origin influences tumor heterogeneity in mouse skin squamous cell carcinoma.

This article reviews the various functions of the skin, its structure, and the impact that damage or disorders can have on both skin function and interpersonal communication, without presenting new experimental findings.

This review discusses the advancements enabled by intravital microscopy in understanding host-parasite interactions in living animals and reports no new clinical results.

This comprehensive review suggests that CD44 signaling plays a significant role in post-natal skin wound healing and scar formation, with potential for therapeutic approaches targeting CD44 to shift from fibrotic scarring towards regenerative healing, including wound regeneration and hair neogenesis.

This review discusses the developmental origins and diversity of dermal fibroblasts, focusing on their roles in epidermal and hair follicle growth, but reports no clinical results.

This review examines the increase in dermatologic conditions related to COVID-19, highlighting direct viral effects, PPE-related issues, and stress-related exacerbations, but reports no new clinical findings.

This study found a high concordance between subject-reported and clinician-reported Fitzpatrick Skin Phototypes, but 14% of subjects misjudged their skin type, often overestimating it.

This review highlights how natural compounds can enhance wound healing by influencing fibroblast behavior and discusses innovative biomimetic engineering and delivery methods. This source emphasizes combining traditional and modern approaches for effective and scar-free healing, while noting challenges in clinical translation.

This review discusses follicular and scarring disorders in skin of color and highlights the need for patient education and tailored therapeutic strategies, but does not report new clinical findings.

This study proposes a model suggesting that the ratio of keratin 15 to keratin 14 in epidermal keratinocytes promotes a progenitor state and opposes differentiation, based on insights from both cell culture and transgenic mouse models.

This dissertation reported that the loss of Ovol2 impairs hair follicle regeneration and wound repair in mice, highlighting its role in regulating directional migration of epithelial cells.

This study found that, in mouse tail epidermis, stem cells rapidly activate and regenerate new progenitors to repair wounds, with mechanisms affecting their proliferation, differentiation, and migration.

In this study, eight healthy dogs showed hair and skin damage, including hair shaft fractures and skin irritation, after repeated application of Clairol Hair Dye Flaxen Blonde.

This study found that a novel in-situ crosslinked self-healing hydrogel made from oxidized Bletilla striata polysaccharide and cationic gelatin enhanced wound healing and showed strong hemostatic performance in animal models, suggesting its potential as an effective wound dressing for skin trauma.

This study observed that melanogenesis in human hair follicles is linked to anagen phases, with melanocyte activity and enzyme expression being region-specific to the nascent bulb.

This study found that people with systemic lupus erythematosus consulted primary care more frequently and with specific clinical features before diagnosis, and it developed a risk prediction model that may help in identifying at-risk individuals.

This review discusses the dynamic, niche-driven regulation of stem cell states in tissue homeostasis and regeneration, focusing on epithelial stem cells in the mammalian skin, intestine, and lung, without providing new experimental results.

This study found that mutant cells in hair follicles can be tolerated or eliminated by surrounding normal tissue, suggesting the potential for wild-type cells to counteract oncogenic mutations.