research Harnessing Mesenchymal Aggregation for Engineered Organ-Level Regeneration: Recent Progress and Perspective
Scientists are using clumps of special stem cells to improve organ repair.
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research Homogenization Theory Captures Macroscopic Flow Discontinuities Across Janus Membranes
The homogenization theory effectively describes how flow behaves differently across asymmetric membranes.
research Matrisomal Components Involved in Regenerative Wound Healing in Axolotl and Acomys: Implications for Biomaterial Development
Certain genes are more active during wound healing in axolotl and Acomys, which could help develop materials that improve human wound healing and regeneration.
research Epithelial-Mesenchymal Micro-Niches Govern Stem Cell Lineage Choices
Different small areas within hair follicles send specific signals that control what type of cells stem cells become.
research Advancing Regenerative Cellular Therapies in Non-Scarring Alopecia
Regenerative cellular therapies show promise for treating non-scarring hair loss but need more research.
research Control by a Hair’s Breadth: The Role of MicroRNAs in the Skin
MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.
research Early Dengue Virus Infection in Human Skin: A Cycle of Inflammation and Infectivity
Chicken feather gene mutation helps understand human hair disorders.
research CD34 Glycoprotein Identifies Putative Stem Cells Located in the Isthmic Region of Canine Hair Follicles
CD34 marks potential stem cells in dog hair follicles.
research Regeneration of Hair and Other Skin Appendages: A Microenvironment-Centric View
The microenvironment, especially mechanical forces, plays a crucial role in hair growth and could lead to new treatments for hair loss.
research Alopecia
Alopecia areata is a reversible, autoimmune-related hair loss that can have significant emotional impact and uncertain treatment effectiveness.
research Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
research Epidermal Stem Cells and Skin Tissue Engineering in Hair Follicle Regeneration
Hair follicle regeneration needs special conditions and young cells.
research Getting Under the Skin of Hair Aging: The Impact of the Hair Follicle Environment
Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.
research KGF And EGF Signaling Block Hair Follicle Induction And Promote Interfollicular Epidermal Fate In Developing Mouse Skin
EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.
research Skin and Hair: Models for Exploring Organ Regeneration
Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.
research Pharmacological Inhibition of Stearoyl CoA Desaturase in the Skin Induces Atrophy of the Sebaceous Glands
Blocking SCD1 in the skin with XEN103 shrinks sebaceous glands in mice.
research A Comparison of Transcriptomic Patterns Measured in the Skin of Chinese Fine and Coarse Wool Sheep Breeds
Fine wool sheep have more genes for wool quality, while coarse wool sheep have more for skin and muscle traits.
research Skin Cell-Derived Extracellular Vesicles: A Promising Therapeutic Strategy for Cutaneous Injury
Skin cell-derived vesicles can help heal skin injuries effectively.
research Developing Human Fetal Skin Demonstrates a Unique Lymphocyte Signature
Fetal skin has unique immune cells different from adult skin.
research DNA Methylation as an Epigenetic Memory Keeper During Skin Development and Regeneration
DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.
research Staining of Human Skin With RGB Trichrome Unveils a Proteoglycan-Enriched Zone in the Hair Dermal Sheath
A new staining method shows a special area in the hair's skin layer with lots of proteoglycans.
research All Roads Lead to the Nucleus: Integration of Signaling, Transcription Factor-Mediated, and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration
The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
research Molecular Regulation and Cellular Heterogeneity in Skin Repair and Hair Follicle Regeneration
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
research Cornification
Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.
research Recreation of a Hair Follicle Regenerative Microenvironment: Successes and Pitfalls
Hair growth environment recreated with challenges; stem cells make successful skin organoids.
research Hair Follicle Stem Cells: Walking the Maze
Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
research Epidermal Development in Mammals: Key Regulators, Signals from Beneath, and Stem Cells
Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
research The Novel Mechanisms and Applications of Exosomes in Dermatology and Cutaneous Medical Aesthetics
Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.
research Unraveling the Link Between Ectodermal Disorders and Primary Immunodeficiencies
Skin abnormalities can indicate immunodeficiency due to shared origins with the immune system.
research Highly Upregulated Lhx2 in the Foxn1−/− Nude Mouse Phenotype Reflects a Dysregulated and Expanded Epidermal Stem Cell Niche
The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.