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    Glossary Skin Aging

    natural process where skin loses elasticity and develops wrinkles

    Skin aging, also known as aging skin or skin ageing, refers to the natural process where the skin undergoes changes over time, leading to wrinkles, loss of elasticity, and thinning. This process is influenced by intrinsic factors like genetics and hormonal changes, as well as extrinsic factors such as UV exposure, pollution, and lifestyle choices.

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    1. Skin Aging and Menopause American Journal of Clinical Dermatology · 2003 · 180 citations
    2. Estrogens and aging skin Dermato-endocrinology · 2013 · 150 citations
    3. Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging International Journal of Molecular Sciences · 2017 · 132 citations
    4. The Pathobiology of Skin Aging American Journal Of Pathology · 2020 · 122 citations
    5. Effect of estrogens on skin aging and the potential role of SERMs Clinical Interventions in Aging · 2007 · 120 citations
    6. Skin connective tissue and ageing Best Practice & Research in Clinical Obstetrics & Gynaecology · 2013 · 77 citations
    7. Skin ageing Menopause International · 2007 · 76 citations
    8. Skin aging: are adipocytes the next target? Aging · 2016 · 70 citations
    9. Air Pollution, Autophagy, and Skin Aging: Impact of Particulate Matter (PM10) on Human Dermal Fibroblasts International Journal of Molecular Sciences · 2018 · 68 citations
    10. The Skin and Inflamm-Aging Biology · 2023 · 60 citations
    11. Skin aging as a mechanical phenomenon: The main weak links Nutrition and healthy aging · 2018 · 41 citations
    12. Biorevitalizing effect of a novel facial serum containing apple stem cell extract, pro‐collagen lipopeptide, creatine, and urea on skin aging signs Journal of Cosmetic Dermatology · 2015 · 36 citations
    13. Recent advances on skin‐resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti‐aging and cancer therapies Journal of Cellular and Molecular Medicine · 2009 · 36 citations
    14. Skin climacteric aging and hormone replacement therapy Journal of cosmetic dermatology · 2006 · 27 citations
    15. Stem Cells in Dermatology and Anti-aging Care of the Skin Facial Plastic Surgery Clinics of North America · 2018 · 23 citations
    16. Getting under the skin of hair aging: the impact of the hair follicle environment Experimental Dermatology · 2020 · 20 citations
    17. Innovations in Skin and Soft Tissue Aging—A Systematic Literature Review and Market Analysis of Therapeutics and Associated Outcomes Aesthetic Plastic Surgery · 2023 · 17 citations
    18. Effectiveness of Extracellular Vesicle Application in Skin Aging Treatment and Regeneration: Do We Have Enough Evidence from Clinical Trials? International Journal of Molecular Sciences · 2025 · 16 citations
    19. Interplay of MicroRNA-21 and SATB1 in Epidermal Keratinocytes during Skin Aging Journal of Investigative Dermatology · 2019 · 16 citations
    20. The regulatory role of the tetrapeptide AcSDKP in skin and hair physiology and the prevention of ageing effects in these tissues – a potential cosmetic role International Journal of Cosmetic Science · 2013 · 13 citations
    21. Targeting the stem cell niche: role of collagen XVII in skin aging and wound repair Theranostics · 2022 · 9 citations
    22. Montagna Symposium 2014—Skin Aging: Molecular Mechanisms and Tissue Consequences 2015 · 9 citations
    23. Effect of conditioned media collected from human amniotic fluid-derived stem cells (hAFSCs) on skin regeneration and photo-aging Tissue Engineering and Regenerative Medicine · 2014 · 9 citations
    24. The Role of PGC-1α in Aging Skin Barrier Function Cells · 2024 · 8 citations
    25. Imbalanced redox dynamics induce fibroblast senescence leading to impaired stem cell pools and skin aging Free Radical Biology and Medicine · 2025 · 7 citations
    26. Toward Elucidating Epigenetic and Metabolic Regulation of Stem Cell Lineage Plasticity in Skin Aging Frontiers in Cell and Developmental Biology · 2022 · 7 citations
    27. The Role of Coenzyme Q10 in Skin Aging and Opportunities for Topical Intervention: A Review. PubMed · 2024 · 6 citations
    28. Association between serum melatonin and skin aging in an urban population of Mongolia Journal of cosmetic dermatology · 2019 · 6 citations
    29. Modulating testosterone pathway: a new strategy to tackle male skin aging? Clinical Interventions in Aging · 2012 · 6 citations
    30. Managing Skin Ageing as a Modifiable Disorder—The Clinical Application of Nourella® Dual Approach Comprising a Nano-Encapsulated Retinoid, Retilex-A® and a Skin Proteoglycan Replacement Therapy, Vercilex® Cosmetics · 2022 · 4 citations