1 citations
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October 2021 in “QJM: An International Journal of Medicine” This study found that platelet-rich plasma prepared using a double-spin method may be more effective for treating female pattern hair loss than single-spin PRP, although VEGF concentration was unaffected by either preparation method.
December 2023 in “PubMed” This study found that both single- and double-spin PRP preparation methods significantly increased thrombocyte counts and improved hair parameters in males with androgenetic alopecia, with the single-spin method showing a more significant increase in thrombocyte count.
January 2025 in “Journal of Bacha Khan Medical College.” This study compared two PRP preparation techniques for treating androgenetic alopecia and found that both methods led to some improvement in hair loss, but further research is suggested due to variations in PRP preparation.
10 citations
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September 2020 in “Archives of Dermatological Research” Both methods improve hair density and thickness; double-spin may be more effective.
July 2025 in “Frontiers in Medicine” In this systematic review and meta-analysis, the authors examined single-spin versus double-spin centrifugation protocols for PRP in patients with androgenic alopecia and found no significant difference in platelet concentration, hair density, or hair types between the protocols.
July 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found no significant differences in platelet concentration or hair growth outcomes between single-spin and double-spin PRP centrifugation methods for treating androgenic alopecia, suggesting that the simpler single-spin approach may be preferable.
July 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this systematic review and meta-analysis, the researchers found no significant difference in platelet concentration, hair density improvement, or changes in terminal and vellus hair rates between single-spin and double-spin PRP centrifugation protocols in treating androgenic alopecia.
1 citations
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January 2017 in “Indian Dermatology Online Journal” This commentary reviews clinical trials on platelet-rich plasma treatments for androgenetic alopecia and emphasizes the need for standardized preparation methods and concentrations; it reports no new clinical results.
October 2025 in “JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH” This study found that both single spin and double spin techniques of PRP preparation significantly improved hair growth in male androgenetic alopecia, with no statistical difference between the methods.
27 citations
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January 2017 in “Indian Dermatology Online Journal” This study found no significant benefit from PRP injections for treating androgenetic alopecia in men, highlighting the need for larger, well-designed trials to assess its effectiveness and safety.
2 citations
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May 2024 in “Cureus” This study found that both single and double spin platelet-rich plasma methods significantly reduced chronic ulcer surface area, with single spin showing notable healing improvements.
November 2025 in “Eduvest - Journal Of Universal Studies” This case report describes a young male patient with androgenetic alopecia who experienced significant hair growth improvement and no side effects after receiving single spin platelet-rich plasma therapy combined with topical minoxidil.
July 2023 in “International journal of trichology” This review concluded that the double-spin PRP preparation method may be more effective than the single-spin technique for treating androgenetic alopecia.
10 citations
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August 2020 in “Dermatologic Therapy” This study found that platelet-rich plasma significantly increased hair diameter in both men and women with androgenetic alopecia but improved hair density only in men.
August 2020 in “Rossiiskii Zhurnal Kozhnykh i Venericheskikh Boleznei” This review analyzes platelet-rich plasma preparation methods for treating androgenetic alopecia but reports no new clinical results, suggesting a need for further research to evaluate efficacy and tolerance.
March 2026 in “Frontiers in Pharmacology” The study concluded that the Exprecell™ device for preparing anticoagulant-free f-PRF increases volume yield and simplifies the process while maintaining biological activity comparable to conventional methods, suggesting potential clinical utility.
1 citations
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April 2021 in “Journal of the American Academy of Dermatology” This retrospective review found that platelet-rich plasma products from FDA-cleared devices for alopecia were inconsistent, highlighting a need for more detailed examination of preparation methods.
January 2022 in “Journal of Cosmetic Dermatology” This study found that PRP injections, prepared using a digital centrifuge with a large-sized sodium citrate tube at low centrifugation speed, significantly improved hair thickness and terminal hair percentage in women with pattern hair loss, with similar results across different preparation methods.
3 citations
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February 2025 in “Life” In this study, significant improvements in skin density and thickness, especially around the lower eyelid, were observed across all age groups using plasma fractions from a single blood draw, indicating that the therapy's effectiveness may be age-independent.
1 citations
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April 2020 in “Plastic and Aesthetic Nursing” This review discusses platelet-rich plasma therapy for nonscarring alopecia and reports no new clinical results; the author recommends more large-scale controlled studies, particularly for scarring alopecia and symptom control.
1 citations
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January 2021 in “Indian Dermatology Online Journal” This expert group provided recommendations for preparing and using platelet-rich plasma in treating androgenetic alopecia, suggesting a manual double-spin method and specific dosing, although further studies on injectable platelet-rich fibrin are needed.
4 citations
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July 2024 in “Cureus” In this report, researchers observed that a single treatment using a combination of hyperdiluted calcium hydroxylapatite, platelet-rich plasma, and hyaluronidase improved neck wrinkles and skin laxity in two patients, indicating preliminary evidence for the safety and efficacy of this novel therapy.
August 2021 in “Journal of emerging technologies and innovative research” This review examines the efficacy of platelet-rich plasma for treating hair loss, highlighting the lack of standardized protocols for PRP preparation and delivery and reporting no new clinical results.
April 2024 in “Skin research and technology” This study found that combining a single SVF injection with PRP sessions did not significantly enhance hair growth outcomes compared to PRP injections alone in patients with androgenetic alopecia.
6 citations
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January 2021 in “Journal of the American Academy of Dermatology” This review discusses the use of platelet-rich plasma for alopecia treatment and notes a lack of data on the consistency of FDA-approved PRP devices in clinical settings.
9 citations
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May 2024 in “Cureus” This review discusses the role of platelet-rich plasma in assisted reproductive technology for enhancing endometrial receptivity and reports promising outcomes.
58 citations
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January 2020 in “International Journal of Molecular Sciences” This review evaluates various kits for isolating platelet-rich plasma using established processing standards and finds they enable compliance with consensus quality criteria; ongoing research is needed to refine these procedures for improved consistency and safety.
7 citations
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June 2019 in “Fayoum University Medical Journal/Fayoum University Medical Journal ” In this study, researchers aimed to investigate the effects of injecting intralesional platelet-rich plasma and vitamin D in patients with vitiligo, focusing on their potential to induce skin pigmentation. Results are not reported in the abstract.
November 2025 in “PARIPEX-INDIAN JOURNAL OF RESEARCH” GFC is more effective than PRP for treating hair loss.
January 2024 in “International Journal of Scientific Research in Science and Technology” This review analyzes Platelet-Rich Plasma therapy for facial aesthetics, discussing its principles, efficacy, safety, and future research directions, but reports no new clinical results.