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    Did you mean Signal Transduction Inhibitor?
    Glossary Signal Transduction Inhibitor

    blocks cell communication pathways to prevent abnormal growth

    A Signal Transduction Inhibitor (STI) is a type of drug that blocks the communication pathways within cells, which are responsible for transmitting signals from the cell surface to the interior. These inhibitors can interfere with the processes that lead to cell growth, division, and survival, making them useful in treating conditions like cancer, where cell signaling pathways are often overactive.

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    1. Nitric Oxide Signal Transduction and Its Role in Skin Sensitization Biomolecules & therapeutics · 2023 · 1 citations
    2. Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne 2009 · 65 citations
    3. Unique Circulating MicroRNA Signatures Distinguish Severe Alopecia Areata from Other Inflammatory Skin Diseases Preprints.org · 2025
    4. MicroRNA control of signal transduction Nature Reviews Molecular Cell Biology · 2010 · 1066 citations
    5. Hair Growth Promoting Effects of Limosilactobacillus reuteri Isolated from Honeybee through Wnt/β-catenin Signal Transduction Journal of the Korean Society of Cosmetology · 2026
    6. Janus Kinase Inhibitors in Dermatology: Part 1 — General Considerations and Applications in Vitiligo and Alopecia Areata Actas Dermo-Sifiliográficas · 2021 · 14 citations
    7. Physiological and transcriptomic analyses of brassinosteroid function in kiwifruit root Environmental and Experimental Botany · 2021 · 8 citations
    8. Overexpression of Smad7 results in severe pathological alterations in multiple epithelial tissues The EMBO Journal · 2002 · 111 citations
    9. The JAK/STAT signaling pathway: from bench to clinic Signal Transduction and Targeted Therapy · 2021 · 489 citations
    10. Expression patterns of the glial cell line–derived neurotrophic factor, neurturin, their cognate receptors GFRα-1, GFRα-2, and a common signal transduction element c-Ret in the human skin hair follicles Journal of The American Academy of Dermatology · 2008 · 18 citations
    11. LncRNA PlncRNA‑1 regulates proliferation and differentiation of hair follicle stem cells through TGF‑β1‑mediated Wnt/β‑catenin signal pathway Molecular Medicine Reports · 2017 · 25 citations
    12. Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways InTech eBooks · 2017 · 1 citations
    13. Unravelling the molecular basis for symbiotic signal transduction in legumes Molecular Plant Pathology · 2006 · 27 citations
    14. Myricetin: A Significant Emphasis on Its Anticancer Potential via the Modulation of Inflammation and Signal Transduction Pathways International Journal of Molecular Sciences · 2023 · 54 citations
    15. A Murine Model for Inducing and Manipulating Hair Follicle Regression (Catagen): Effects of Dexamethasone and Cyclosporin A Journal of Investigative Dermatology · 1994 · 124 citations
    16. Molecular basis of hypohidrotic ectodermal dysplasia: an update Journal of Applied Genetics · 2015 · 85 citations
    17. Chrousos syndrome: from molecular pathogenesis to therapeutic management European Journal of Clinical Investigation · 2015 · 47 citations
    18. Linking diet to acne metabolomics, inflammation, and comedogenesis: an update Clinical, Cosmetic and Investigational Dermatology · 2015 · 138 citations
    19. Exercise activates the PI3K-AKT signal pathway by decreasing the expression of 5α-reductase type 1 in PCOS rats Scientific reports · 2018 · 28 citations
    20. 1407 ANDROGENETIC ALOPECIA, PROSTATE VOLUME AND URINARY SYMPTOMS. IS THERE A RELATIONSHIP? A CASE-CONTROL STUDY The Journal of Urology · 2010
    21. Peripheral blood gene expression in alopecia areata reveals molecular pathways distinguishing heritability, disease and severity Genes and Immunity · 2010 · 20 citations
    22. Hair Follicle Pigmentation 2005 · 450 citations
    23. Transcriptome Profile at Different Physiological Stages Reveals Potential Mode for Curly Fleece in Chinese Tan Sheep PloS one · 2013 · 55 citations
    24. Analysis of Skin Regeneration and Barrier-Improvement Efficacy of Polydeoxyribonucleotide Isolated from Panax Ginseng (C.A. Mey.) Adventitious Root Molecules · 2023 · 17 citations
    25. Differential Expression of Proteins Associated with the Hair Follicle Cycle - Proteomics and Bioinformatics Analyses PLOS ONE · 2016 · 10 citations
    26. Proteome Analysis of Alpine Merino Sheep Skin Reveals New Insights into the Mechanisms Involved in Regulating Wool Fiber Diameter International journal of molecular sciences · 2023
    27. A systematic simulation-based meta-analytical framework for prediction of physiological biomarkers in alopecia Journal of Biological Research · 2019 · 11 citations
    28. Hair Follicle Culture Methods in pharmacology and toxicology · 2012
    29. The HEDGEHOG-GLI1 pathway is important for fibroproliferative properties in keloids and as a candidate therapeutic target Communications biology · 2023
    30. Novel insights into the molecular mechanisms underlying generalized glucocorticoid resistance and hypersensitivity syndromes Hormones · 2017 · 15 citations