62 citations,
November 2009 in “Aging Cell” Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.
49 citations,
October 2009 in “Cancer research” Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.
6 citations,
January 2016 in “Journal of Stem Cell Research & Therapy” Notch1 signaling is crucial for improving wound healing and skin regeneration by affecting stem cell behavior.
54 citations,
January 2016 in “Cell reports” Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.
61 citations,
June 2018 in “Proceedings of the National Academy of Sciences of the United States of America” Light can turn on hair growth cells through a nerve path starting in the eyes.
143 citations,
September 2008 in “Experimental gerontology” Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
1 citations,
March 2023 in “Aggregate” A new hydrogel with micronized amnion helps achieve better, scar-free skin healing.
12 citations,
May 2014 in “International Journal of Molecular Medicine” Chrysanthemum zawadskii extract helps hair grow by stimulating hair cells.
173 citations,
January 2014 in “Nature Cell Biology” Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.
20 citations,
February 2017 in “International Journal of Dermatology” Platelet-based therapies using a patient's own blood show promise for skin and hair regeneration but require more research for confirmation.
6 citations,
June 2013 in “British Journal of Dermatology” Intense pulsed light treatment mainly damages pigmented hair parts but spares stem cells, allowing hair to regrow.
25 citations,
November 2014 in “British Journal of Dermatology” Certain transporters are found in human hair follicles and may affect hair growth and loss.
4 citations,
May 2014 in “Biochemical Society Transactions” Environmental cues can change the fate and function of epithelial cells, with potential for cell therapy.
30 citations,
April 2013 in “Journal of Investigative Dermatology” Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.
62 citations,
April 2009 in “British Journal of Dermatology” Epidermal stem cells could lead to new treatments for skin and hair disorders.
260 citations,
June 2011 in “Cell” Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.
240 citations,
April 2011 in “Pigment Cell & Melanoma Research” Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
1039 citations,
February 2009 in “Nature Reviews Molecular Cell Biology” Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
48 citations,
July 2008 in “Acta Biochimica et Biophysica Sinica” Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.
19 citations,
June 2008 in “Journal of Investigative Dermatology” HPV genes in mice improve ear tissue healing by speeding up skin growth and repair.
499 citations,
September 2011 in “Cell” Fat-related cells are important for initiating hair growth.
14 citations,
February 2014 in “Experimental Cell Research” The conclusion is that teeth, hair, and claws have similar stem cell niches, which are important for growth and repair, and more research is needed on their regulation and potential markers.
165 citations,
June 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
10 citations,
September 2018 in “Regenerative Medicine” New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.
12 citations,
January 2009 in “Stembook” Improved understanding of stem cell mechanisms can enhance skin tissue engineering.
80 citations,
May 2011 in “Nature Cell Biology” New methods have greatly improved our understanding of stem cell behavior and roles in the body.
2 citations,
January 2016 in “Springer eBooks” Fat tissue stem cells show promise for repairing different body tissues and are being tested in clinical trials.
1 citations,
June 2023 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Vitamin D helps skin stem cells heal wounds by working with a key skin protein.
119 citations,
March 2020 in “Frontiers in Bioengineering and Biotechnology” Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.
29 citations,
March 2020 in “Stem Cell Research & Therapy” Fat stem cells from diabetic mice can help heal skin wounds in other diabetic mice.