16 citations,
February 2019 in “Gene” Researchers found a good way to isolate hair follicle stem cells from newborn goats for further study.
14 citations,
April 2011 in “Cell Proliferation” Scientists can grow human hair follicle stem cells in a lab without changing their nature, which could help treat hair loss.
11 citations,
May 2015 in “Stem Cells Translational Medicine” Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.
11 citations,
January 2013 in “Methods in molecular biology” The method allows for 3D tracking of hair follicle stem cells and shows they can regenerate hair for up to 180 days.
3 citations,
August 2014 in “Cellular reprogramming” Hair follicle stem cells need all reprogramming factors to become pluripotent.
1 citations,
January 2023 in “In vivo/In Vivo” Box A of HMGB1 can improve stem cell function, aiding anti-aging therapy.
1 citations,
May 2022 in “Frontiers in medicine” Metformin helps improve skin regeneration by increasing the growth of skin stem cells.
December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” MicroRNA-205 helps hair grow by changing the stiffness and contraction of hair follicle cells.
42 citations,
March 2008 in “Molecular and Cellular Endocrinology” Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.
39 citations,
October 2013 in “Plastic and Reconstructive Surgery” Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.
4 citations,
January 2018 in “Microscopy research” Scientists found markers called CD34 and CD200 that help identify stem cells in mouse and human hair follicles.
44 citations,
July 2016 in “Stem Cells Translational Medicine” Scientists discovered that certain stem cells from mice and humans can be used to grow new hair follicles and skin glands when treated with a special mixture.
23 citations,
January 2015 in “Stem cells international” Coating surfaces with human hair keratin improves the growth and consistency of important stem cells for medical use.
10 citations,
June 2016 in “Cell Transplantation” Sebaceous glands can help harvest hair follicle stem cells to regenerate skin and hair.
13 citations,
July 2020 in “World journal of stem cells” Vitamin D and calcium are important for skin stem cell function and wound healing.
7 citations,
November 2016 in “Oncotarget” UV exposure reduces Lgr6+ stem cells in mouse skin and they don't significantly contribute to skin cancer development.
550 citations,
December 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.
479 citations,
June 2014 in “Science” Epithelial stem cells can adapt and help in tissue repair and regeneration.
144 citations,
September 2012 in “Genes & development” Aging causes skin stem cells to work less effectively.
143 citations,
May 2017 in “Nature cell biology” Wounded skin cells can revert to stem cells and help heal.
137 citations,
April 2015 in “Nature Reviews Molecular Cell Biology” Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.
129 citations,
July 2019 in “Stem Cell Research & Therapy” Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
117 citations,
March 2017 in “Nature Communications” Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.
105 citations,
October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.
62 citations,
November 2009 in “Aging Cell” Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.
58 citations,
August 2015 in “The Indonesian Biomedical Journal” Different types of stem cells help maintain and heal skin.
36 citations,
September 2009 in “Journal of Cellular and Molecular Medicine” New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
28 citations,
March 2010 in “Histochemistry and Cell Biology” Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.
11 citations,
July 2012 in “Experimental dermatology” Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.
9 citations,
January 2017 in “Elsevier eBooks” Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.