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90-120 / 1000+ results research 042 Characterization of Pathogenic CD8+ T Cells in an adoptive transfer Mouse Model of Alopecia Areata in C3H/HeJ mice
Certain CD8+ T cells attack hair follicles in alopecia areata, suggesting they could be targeted for treatment.
research Expression and function of FGFs-4, -8, and -9 suggest functional redundancy and repetitive use as epithelial signals during tooth morphogenesis
This study suggests that fibroblast growth factors FGF-4, FGF-8, and FGF-9 may play redundant roles as signals in epithelial-mesenchymal interactions during multiple stages of tooth development in mice.
research Neutralization of IL-8 Prevents the Induction of Dermatologic Adverse Events Associated with the Inhibition of Epidermal Growth Factor Receptor
This study found that locally injected zalutumumab in healthy volunteers induced a papulopustular rash similar to systemic EGFR inhibitors, and that IL-8 inhibition reduced this dermatological side effect.
research Hypohidrotic Ectodermal Dysplasia with c.28delG Mutation in Ectodysplasin A Gene and Severe Atopic Dermatitis Treated Successfully with Tofacitinib
In this study, patients with specific skin and scalp conditions, including eczematous lesions, showed significant improvement after two weeks of oral tofacitinib treatment, as evidenced by changes in the trunk lesions.
research Folliculotropic CD8+ mycosis fungoides associated with diffuse mucosal involvement
This report describes a rare case of folliculotropic and syringotropic CD8 mycosis fungoides with unusual widespread mucosal involvement.
research A homozygous nonsense mutation identified in COL7A1 in a family with autosomal recessive dystrophic epidermolysis bullosa
In this study, researchers identified a recurrent nonsense mutation, c.409C>T (p.Arg137*), in the COL7A1 gene through whole exome sequencing in a family with autosomal recessive dystrophic epidermolysis bullosa, demonstrating the importance of this method for diagnosing genetically complex conditions.
research Preparation and Evaluation of Self-emulsifying Drug Delivery System (SEDDS) of Cepharanthine
research 50842 Mohs micrographic surgery for nail-unit squamous cell carcinoma
research Read-Through for Nonsense Mutations in Type XVII Collagen‒Deficient Junctional Epidermolysis Bullosa
This article discusses junctional epidermolysis bullosa caused by COL17 deficiency, noting a lack of experimental therapies and the impact of nonsense mutations, but it reports no new clinical results.
research egfl6 expression in the pharyngeal pouch is dispensable for craniofacial development
This study suggests that egfl6 expression in the pharyngeal pouches is not essential for craniofacial development in zebrafish.
research Editorial: Software survey section
research Subject Index, Vol. 7,1994
research Tellurium, Selenium, Antimony and Arsenic in Scalp Hair
research 0497 Periderm without IRF6: To be or not to be
research DataSheet1_BBS7–SHH Signaling Activity Regulates Primary Cilia for Periodontal Homeostasis.csv
This study found that downregulation of BBS7 in periodontal ligament cells was associated with reduced Sonic hedgehog signaling, which plays a crucial role in maintaining PDL homeostasis.
research Pvalb8, a Type of Oncomodulin, Regulates Neuromast Development and Auditory Function in Zebrafish
In this study, researchers identified that the oncomodulin protein lineage, specifically the gene pvalb8, plays a crucial role in the development and function of auditory hair cells in zebrafish by promoting cell proliferation through the Wnt signaling pathway.
research Subject Index
This subject index from the book "Stem Cells in Toxicology and Medicine" offers no new research results.
research Site of beige (bg) and leaden (ln) pigment gene expression determined by recombinant embryonic skin grafts and aggregation mouse chimaeras employing sash (Wsh) homozygotes
This study found that in chimaeric mice models, the pigment distribution and pattern were influenced by the sash genotype, demonstrating the melanocyte-autonomous nature of the beige and leaden loci.
research If I Were You
The document's conclusion cannot be summarized because the content is not available.
research Formulation and evaluation of self-nanoemulsifying drug delivery system for improved oral delivery of exemestane hydrochloride
This study explored the development of a self nanoemulsifying drug delivery system to enhance the solubility and oral bioavailability of exemestane HCl for breast cancer therapy.
research NUDT15,FTO, andRUNX1genetic variants and thiopurine intolerance among Japanese patients with inflammatory bowel diseases
This study found that among Japanese IBD patients, the NUDT15 p.Arg139Cys variant was significantly associated with thiopurine-induced leukopenia and severe hair loss, suggesting its genotyping is important for predicting these adverse events.
research Mind the Gap: A Solution to the Robustness Problem of Turing Patterns Through Patterning Mode Isolation
This study explored a mechanism for making Turing pattern formations more predictable and robust by isolating pattern modes to prevent their sensitivity to initial conditions, which can lead to different outcomes from minor initial changes.
research Video5_BBS7–SHH Signaling Activity Regulates Primary Cilia for Periodontal Homeostasis.MP4
This study suggests that the downregulation of BBS7 in occlusal hypofunctional periodontal ligament impairs Shh signaling, which is essential for maintaining periodontal ligament homeostasis.
research Topical Delivery of Tofacitinib in Dermatology: The Promise of a Novel Therapeutic Class Using Biodegradable Dendritic Polyglycerol Sulfates
The researchers reported that dPGS-PCL as a carrier improved the penetration of tofacitinib in an ex-vivo human skin model compared to free tofacitinib, but did not show significant differences in inhibiting IL-6 and IL-8 during short incubation.
research DataSheet3_BBS7–SHH Signaling Activity Regulates Primary Cilia for Periodontal Homeostasis.csv
This study found that BBS7 is downregulated in occlusal hypofunctional periodontal ligament, suggesting it plays a crucial role in maintaining Shh signaling for PDL homeostasis.
research Recurrent MBTPS2 variant c.970+5G>A in IFAP syndrome: a mutational hotspot
In this study, researchers identified a recurrent MBTPS2 splice-site variant as a mutational hotspot in IFAP syndrome across diverse families, with phenotype severity suggesting the influence of additional modifiers.
research POSTTEST: EXPIRATION DATE: OCTOBER 2011
This abstract contains subscription and access information for Wolters Kluwer Health journals but reports no research findings.
research Doxazosin + finasteride in BPH with TPV ??? 25mL
research ISSUES OF IMPLEMENTATION OF SYSTEM OF CONTROL IN SUSTAINABLE FINANCIAL AND ECONOMIC MANAGEMENT OF INDUSTRIAL ENTERPRISES
This study highlights how economic systems facing global uncertainties require effective management based on sustainable development principles, emphasizing adaptive management and scientific modeling to enhance financial and economic stability within enterprises.